Utility of trabecular bone rating within the analysis of osteoporosis.
Curr Opin Endocrinol Diabetes Obes. 2017 Dec;24(6):402-410
Authors: Martineau P, Silva BC, Leslie WD
PURPOSE OF REVIEW: Trabecular bone rating (TBS) is a lumbar backbone dual-energy absorptiometry texture index which gives data on skeletal high quality partially unbiased of bone mineral density (BMD). A physique of labor has emerged demonstrating the connection between TBS and fracture threat, with decrease TBS values related to elevated threat for osteoporotic fracture in postmenopausal ladies and older males. TBS is derived from commonplace DXA photographs; nonetheless, the data supplied by TBS is complementary to that supplied by BMD. On this article, we overview the present state of TBS and its evolving function within the evaluation and administration of osteoporosis, with specific emphasis on the literature of the earlier 12 months.
RECENT FINDINGS: TBS-adjusted The Fracture Danger Evaluation software (FRAX) possibilities improve fracture threat prediction in contrast with standard FRAX predictions. TBS has been discovered to raised categorize fracture threat and assists in FRAX-based therapy choices, notably for sufferers near an intervention threshold. Nevertheless, change in lumbar backbone TBS whereas present process antiresorptive therapy shouldn’t be a helpful indicator of antifracture impact.
SUMMARY: Lumbar backbone TBS is a not too long ago developed image-based software program approach for skeletal evaluation, complementary to standard BMD, which has been proven to be clinically helpful as a fracture threat prediction software.
PMID: 28857846 [PubMed – indexed for MEDLINE]