Utility of DXA screening for prognosis of osteoporosis in US veterans aged 70 years and older.
J Investig Med. 2018 02;66(2):298-303
Authors: Khatib J, Stote Okay, Gosmanov AR
Twin vitality X-ray absorptiometry (DXA) is really helpful for osteoporosis screening in males aged 70?years and older however supportive information is restricted. The intention of this research was to find out the efficacy of DXA for the prognosis of elevated fragility on this group of topics. We retrospectively recognized males aged 70?years and older with out prior historical past of fracture and/or situations predisposing to low bone mineral density (BMD) who attended the VA endocrinology clinic and carried out DXA for osteoporosis screening. We analyzed the connection between BMD and demographic, anthropometric information and biochemical parameters utilizing linear regression fashions. Out of 55 topics recognized, 13 (24%) males had regular BMD, 30 (54%) had osteopenia and 12 (22%) had a prognosis of osteoporosis based mostly on the femoral neck (FN) T-score. Lumbar backbone T-scores had been regular in all three teams. Weight and physique mass index (BMI) had been considerably greater within the regular BMD group in contrast with the osteopenia and osteoporosis teams (p<zero.001). After changes for age, weight, BMI, vitamin D concentrations, and diabetes standing, variations within the FN BMD among the many teams remained important (p<zero.001). Primarily based on the Fracture Danger Evaluation Software (FRAX) rating calculations in 43 non-osteoporotic sufferers, 15 sufferers with osteopenia had a 10-year hip fracture likelihood ?three%. Screening with DXA in male US veterans aged 70?years and older with out recognized osteoporosis threat elements revealed that as much as 50% of males might qualify for diagnostic workup to find out the etiology of low BMD and/or to satisfy standards to provoke pharmacological remedy to scale back future fracture threat.
PMID: 28974557 [PubMed – indexed for MEDLINE]