19 Harley St, London, W1G 9QJ, UK

Usefulness of diffusion-weighted imaging of breast tumors: quantitative and visual assessment

PURPOSE: We evaluated the usefulness of quantitative and visual assessment of diffusion-weighted imaging (DWI) of breast tumors to distinguish malignant from benign tumors. MATERIALS AND METHODS: The DWI findings of 106 breast lesions (15 benign, 91 malignant) were retrospectively analyzed. The mean apparent diffusion coefficient (ADC) value for each lesion was calculated using b values of 250, 500, 750, and 1000 s/mm(2) as a quantitative assessment. We visually evaluated the signal intensity of each breast lesion on the basis of a spinal signal intensity in DWI (b = 1000 s/mm(2)) and compared the mean ADC values using a threshold mean ADC +1.65 x standard deviation (SD) for malignant and benign breast lesions. Obviously strong signal intensity of the lesion relative to that of the spinal cord on DWI signifies malignancy. RESULTS: The mean ADC value for benign lesions (1.50 +/- 0.38 x 10(-3) mm(2)/s) was significantly higher than that for malignant lesions (0.98 +/- 0.19 x 10(-3) mm(2)/s), with 94.5% sensitivity, 80% specificity, and 92.5% accuracy. Sensitivity for visual assessment was 91.5%, specificity was 33.3%, and total accuracy was 82.5%. CONCLUSION: ADC values, but not visual assessment, may be useful for differentiating benign and malignant breast tumors

Keywords : Adult,Aged,Aged,80 and over,Biopsy,Breast Neoplasms,Contrast Media,diagnosis,Diffusion,Diffusion Magnetic Resonance Imaging,Female,Humans,Japan,methods,Middle Aged,pathology,Radiology,Retrospective Studies,Sensitivity and Specificity,Spinal Cord,Universities,, Diffusionweighted,Imaging,Breast, lower back pain clinic london

Date of Publication : 2011 Jul

Authors : Inoue K;Kozawa E;Mizukoshi W;Tanaka J;Saeki T;Sakurai T;Kimura F;

Organisation : Department of Radiology, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka 350-1298, Japan. kaiji@saitama-med.ac.jp

Journal of Publication : Jpn J Radiol

Pubmed Link : https://www.ncbi.nlm.nih.gov/pubmed/21786099

The London Spine Unit : Harley Street UK. Specialists in Cutting Edge Technologies for Spinal Surgery

Make an Appointment 

Trustpilot Reviews
Doctify Reviews
Top Doctor Reviews

Usefulness of diffusion-weighted imaging of breast tumors quantitative and visual assessment | Botox neck

What our patients say ...

Consultant Spine Surgeon
Consultant Spine Surgeon
Consultant Spine Surgeon

This surgical technique consists of a percutaneous approach for the treatment of small to medium size hernias of the intervertebral disc by laser energy. The main objective is to reduce the intradiscal pressure in the nucleus pulposus

Laser Disc Surgery can be performed under local anaesthetic as a day case at our centre on the prestigious Harley Street.
What is London spine unit and How it Works

The London Spine Unit was established in 2005 and has successfully treated over 5000 patients. All conditions are treated.

treatment of all spinal disorders

The London Spine Unit specialises in Minimally Invasive Treatments allowing rapid recovery and return to normal function

Trusted by patients worldwide

The London Spine Unit provides the highest quality care to all patients and has VIP services for those seeking exceptional services

If you have any emergency Doctor’s need, simply call our 24 hour emergency

Your personal case manager will ensure that you receive the best possible care.

Call Now 

+44 844 589 2020
+44 203 973 8810