The London Spine Unit Specialists have performed many Spinal Ozone Treatments.

Application of ozone gas in the epidural space of patientsvia spinal endoscopy is apparently safe and reveals a tendency toward positive effect, at least at a 6-month-follow-up, and especially in patients with non-neuropathic pain – even when chronic and otherwise refractory. The results suggest that epidural ozone might be a therapeutic option for persistent low back pain in the future, but controlled studies are still required to prove its efficacy.

More commonly, Ozone is injected into a degenerate disc for pain relief by removing inflammatory mediators by a process of oxidation.

Ozone therapy is especially effective in diseases of the vertebral area, especially in herniated discs.
The herniated disc takes place when the intervertebral disc moves to the nerve root and compresses or clamps the nerve. As a result, neurotoxic substances are secreted that irritate the nerve root and inflammatory and vascular phenomena that affect the surrounding tissues, which cause the pain associated with a hernia.

This is where ozone acts, improving the oxygen supply in the affected area and getting rid of pain and inflammation since it neutralizes and inhibits the production of neurotoxic substances and modulates the immune response. Ozone also dries the part of the disc that protrudes, which leads to its reduction or even disappearance.