19 Harley St, London, W1G 9QJ, UK

What Is Platelet Rich Plasma (PRP) And What Is It Used For?

Platelets are found in your blood. They are the smallest cells in the blood and are responsible for clotting the blood and stopping bleeding. They contain a variety of natural substances that promote healing. By centrifuging blood at high speed it is possible to separate the different components. Being the smallest cells, platelets will remain in the plasma. This fraction of blood can be used to heal areas of damage in your body. There is no consensus on the definition of PRP. Some researchers have suggested that PRP should be understood as the fraction with platelet concentration 3 to 5 times higher than the normal level. However, the most defended definition at the present time is that which characterizes it as a volume of autologous plasma containing a platelet concentration higher than the basal level (150,000-350,000/l).

Depending on the used system, the concentration of platelets, leukocytes, and factors of growth of the preparation will vary.

Consequently, the PRP nomenclature encompasses the different fractions that can be obtained in function of the used method: preparation rich in growth factors, plasma rich in platelets and growth factors, platelet-rich plasma, platelet-poor plasma and rich in leukocytes, platelet-rich and poor in leukocytes.

Mechanism of action

PRP owes its therapeutic interest to the instrumental decisive role of platelets in the healing process and repair of a tissue wound. There are distinguished 3 phases: inflammation, proliferation, and remodeling, in which all the Growth Factors contained in the PRP intervene. Platelets play an important role by functioning as a carrier vehicle for growth factors and of other proteins contained in their alpha granules. These substances will be concentrated and deposited in the place of the wound, exposing and orienting a physiological concentration of proteins that will intervene accelerating and favoring the repair and regeneration process.

PRP plays a powerful osteoinductive role, being able to accelerate the consolidation of fractures or osteointegrate quickly and efficiently different types of bone implants. It should be noted that the PRP has a place in other fields such as dental and maxillofacial surgery, orthopedics, otorhinolaryngology, plastic surgery, neurosurgery, and periodontics. In orthopaedics, PRP can be injected into joints, tendons or wounds to promote healing and reduce inflammation.

Platelet rich plasma, commonly referred to as “PRP’, is a non-operative, permanent solution for conditions such as arthritis. Utilising the body’s natural healing process, Platelet Rich Plasma therapy is a concentration of platelets that are injected into the damaged ligaments, tendons, and joints to promote tissue repair and accelerate healing.

Intradiscal PRP is an outpatient procedure that uses the patient’s own blood platelet cells to address the underlying issue of disc health, rather than merely alleviate disease symptoms.

Specialist Doctors

Consultant Spine Surgeon
Consultant Spine Surgeon
Consultant Spine Surgeon

What our patients say ...

Consultant Spinal Surgeon

Specialist in  Spinal Surgery

Consultant Spinal Surgeon

Specialist in Spinal Deformity Surgery.

Consultant Spinal Anaesthetist

Specialist in Anaesthesia for Spinal Surgery.

Consultant Spinal Surgeon

Specialist in Minimally Invasive Spinal Surgery and Medical Director of The Spine Unit

Consultant Spinal Surgeon

Specialist in Spinal Surgery and previously worked as a consultant in Norway

Consultant Spinal Surgeon
Specialist in Neurological disorders affecting the spine. Treats spinal cord problems.
What is London spine unit and How it Works

The London Spine Unit was established in 2005 and has successfully treated over 5000 patients. All conditions are treated.

treatment of all spinal disorders

The London Spine Unit specialises in Minimally Invasive Treatments allowing rapid recovery and return to normal function

Trusted by patients worldwide

The London Spine Unit provides the highest quality care to all patients and has VIP services for those seeking exceptional services

What our patients say ...

Contact London spine Unit

This surgical technique consists of a percutaneous approach for the treatment of small to medium size hernias of the intervertebral disc by laser energy. The main objective is to reduce the intradiscal pressure in the nucleus pulposus
Laser Disc Surgery can be performed under local anaesthetic as a day case at our centre on the prestigious Harley Street.

Laser Spine Surgery Articles

Application of n-HA/PA66 composite artificial vertebral body in anterior reconstruction of lower cervical spine fracture and dislocation | Hip osteoarthritis
Assessment of adjacent-segment mobility after cervical disc replacement versus fusion RCT with 1 year's results | Disc replacement side effects new
Acute Changes in Mentation in a Patient with Hepatic Cirrhosis Treated with High Doses of Dexamethasone | Total disc replacement
Age-Related Loss of Lumbar Spinal Lordosis and Mobility - A Study of 323 Asymptomatic Volunteers | Chest pain chondritis
Using precisely controlled bidirectional orthopedic forces to assess flexibility in adolescent idiopathic scoliosis comparisons between push-traction film, supine side bending,
Sub-grouping patients with non-specific low back pain based on cluster analysis of discriminatory clinical items | Temporal tendonitis

If you have any emergency Doctor’s need, simply call our 24 hour emergency

Your personal case manager will ensure that you receive the best possible care.

Call Now 

+44 844 589 2020
+44 203 973 8810