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Platelets are found in your blood. They are the smallest cells in the blood and are responsible for clotting the blood and stopping bleeding. They contain a variety of natural substances that promote healing. By centrifuging blood at high speed it is possible to separate the different components. Being the smallest cells, platelets will remain in the plasma. This fraction of blood can be used to heal areas of damage in your body. There is no consensus on the definition of PRP. Some researchers have suggested that PRP should be understood as the fraction with platelet concentration 3 to 5 times higher than the normal level. However, the most defended definition at the present time is that which characterizes it as a volume of autologous plasma containing a platelet concentration higher than the basal level (150,000-350,000/l).
Depending on the used system, the concentration of platelets, leukocytes, and factors of growth of the preparation will vary.
Consequently, the PRP nomenclature encompasses the different fractions that can be obtained in function of the used method: preparation rich in growth factors, plasma rich in platelets and growth factors, platelet-rich plasma, platelet-poor plasma and rich in leukocytes, platelet-rich and poor in leukocytes.