The article presents a study that investigates the effectiveness of tranexamic acid (TXA) in reducing intraoperative bleeding in dogs undergoing spinal decompression surgery for intervertebral disc extrusion (IVDE). The surgical technique used in the study was hemilaminectomy associated with intervertebral disc fenestration (HF). Sixteen dogs with IVDE were included in the study, with eight dogs receiving TXA and eight dogs receiving a saline solution as a control. The study found that the dogs in the TXA group had significantly lower blood loss and better visualization during surgery compared to the control group. However, a severe arterial thromboembolic complication was observed in one dog in the TXA group. Overall, the results suggest that intraoperative tranexamic acid can effectively reduce bleeding and improve operative visualization in dogs with IVDE undergoing spinal decompression surgery
Summarised by Mr Mo Akmal – Lead Spinal Surgeon
The London Spine Unit : most advanced spinal facility on Harley Street UK
Published article
Hemilaminectomy associated with intervertebral disc fenestration (HF) is the most used spinal decompression surgical technique for the treatment of intervertebral disc extrusion (IVDE). The surgical procedure can be hampered by excessive bleeding from the venous sinuses; however, tranexamic acid intravenously (IV) is a possible adjunct to hemostasis in these patients. This study aimed to verify the effectiveness of tranexamic acid in reducing intraoperative bleeding in dogs with thoracolumbar…
Lumbar Decompression Surgery Expert. Best Spinal Surgeon UK
Top Companion Anim Med. 2023 Oct 4:100820. doi: 10.1016/j.tcam.2023.100820. Online ahead of print.ABSTRACTHemilaminectomy associated with intervertebral disc fenestration (HF) is the most used spinal decompression surgical technique for the treatment of intervertebral disc extrusion (IVDE). The surgical procedure can be hampered by excessive bleeding from the venous sinuses; however, tranexamic acid intravenously (IV) is a,
Top Companion Anim Med. 2023 Oct 4:100820. doi: 10.1016/j.tcam.2023.100820. Online ahead of print.
ABSTRACT
Hemilaminectomy associated with intervertebral disc fenestration (HF) is the most used spinal decompression surgical technique for the treatment of intervertebral disc extrusion (IVDE). The surgical procedure can be hampered by excessive bleeding from the venous sinuses; however, tranexamic acid intravenously (IV) is a possible adjunct to hemostasis in these patients. This study aimed to verify the effectiveness of tranexamic acid in reducing intraoperative bleeding in dogs with thoracolumbar and lumbar IVDE submitted to HF. Sixteen dogs with IVDE undergoing HF were included. These were distributed into a TXA group (tranexamic acid 20 mg/kg IV bolus, followed by 2 mg/kg/h IV continuous infusion) (n=8) and a control group, with saline solution (n=8). Blood loss was measured using the gravimetric method. The difficulty of operative visualization due to bleeding was classified by the surgeon. Median blood loss (%) in patients in the TXA group was lower than those in the control group (2.75 ± 1.23 and 4.99 ± 4.44, respectively) (p=0.028). Intraoperative visualization difficulty due to bleeding occurred in 10 patients in the control group, and in no patients in the TXA group. A severe arterial thromboembolic complication was recorded, potentially due to tranexamic acid. The use of intraoperative tranexamic acid was effective in reducing bleeding and facilitating operative visualization in dogs with IVDE undergoing hemilaminectomy and intervertebral disc fenestration.
PMID:37802243 | DOI:10.1016/j.tcam.2023.100820
The London Spine Unit : most advanced spinal facility on Harley Street UK
Read the original publication:
TRANEXAMIC ACID IN REDUCING INTRAOPERATIVE BLEEDING IN DOGS UNDERGOING THORACOLUMBAR AND LUMBAR HEMILAMINECTOMY AND INTERVERTEBRAL DISC FENESTRATION
