151 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: laminectomy These pubmed results were generated on 2012/06/23 PubMed, a service of the National Library of Medicine, includes over 15 million citations for biomedical articles back to the 1950’s. These citations are from MEDLINE…

146 new pubmed citations were retrieved for your search.
Click on the search hyperlink below to display the complete search results:


These pubmed results were generated on 2012/03/10

PubMed, a service of the National Library of Medicine, includes over 15 million
citations for biomedical articles back to the 1950’s.
These citations are from MEDLINE and additional life science journals.
PubMed includes links to many sites providing full text articles and other related resources.

Cost per quality-adjusted life year gained of laminectomy and extension of instrumented fusion for adjacent-segment disease: defining the value of surgical intervention.

J Neurosurg Spine. 2011 Nov 4;

Authors: Adogwa O, Parker SL, Shau DN, Mendenhall SK, Devin CJ, Cheng JS, McGirt MJ

Object Over the past decade, there has been a dramatic increase in the number of spinal fusions performed in the US and a corresponding increase in the incidence of adjacent-segment disease (ASD). Surgical management of symptomatic ASD consists of decompression of neural elements and extension of fusion. It has been shown to have favorable long-term outcomes, but the cost-effectiveness remains unclear. In this study, the authors set out to assess the cost-effectiveness of revision surgery in the treatment of ASD over a 2-year period. Methods Fifty patients undergoing neural decompression and extension of fusion construct for ASD-associated back and leg pain were included in the study. Two-year total back-related medical resource utilization, missed work, and health state values (quality-adjusted life years [QALYs], calculated from the EQ-5D with US valuation) were assessed. Two-year resource use was multiplied by unit costs based on Medicare national allowable payment amounts (direct cost), and patient and caregiver workday losses were multiplied by the self-reported gross-of-tax wage rate (indirect cost). Mean total 2-year cost per QALY gained after revision surgery was assessed. Results The mean (± SD) interval between prior fusion and revision surgery for ASD was 3.07 ± 2.02 years. A mean cumulative 2-year gain of 0.76 QALYs was observed after revision surgery. The mean total 2-year cost of extension of fusion constructs was $47,846 ± $32,712 (surgery cost: $24,063 ± $300; outpatient resource utilization cost: $4175 ± $3368; indirect cost: $19,607 ± $32,187). Revision decompression and extension of fusion was associated with a mean 2-year cost per QALY gained of $62,955. Conclusions In the authors’ practice, revision decompression and extension of fusion provided a significant gain in health state utility for patients with symptomatic ASD, with a 2-year cost per QALY gained of $62,995. When indicated, revision surgery for ASD is a valuable treatment option for patients experiencing back and leg pain secondary to ASD. The findings provide a value measure of surgery that can be compared with future cost-per-QALY-gained studies of medical management or alternative surgical approaches.

PMID: 22054637 [PubMed – as supplied by publisher]

Minimally invasive treatment of lumbar spinal stenosis with a novel interspinous spacer.

Clin Interv Aging. 2011;6:227-33

Authors: Shabat S, Miller LE, Block JE, Gepstein R

PURPOSE: To assess the safety and effectiveness of a novel, minimally invasive interspinous spacer in patients with moderate lumbar spinal stenosis (LSS).
METHODS: A total of 53 patients (mean age, 70 ± 11 years; 45% female) with intermittent neurogenic claudication secondary to moderate LSS, confirmed on imaging studies, were treated with the Superion(®) Interspinous Spacer (VertiFlex, Inc, San Clemente, CA) and returned for follow-up visits at 6 weeks, 1 year, and 2 years. Study endpoints included axial and extremity pain severity with an 11-point numeric scale, Zurich Claudication Questionnaire (ZCQ), back function with the Oswestry Disability Index (ODI), health-related quality of life with the Physical Component Summary (PCS) and Mental Component Summary (MCS) scores from the SF-12, and adverse events.
RESULTS: Axial and extremity pain each decreased 54% (both P < 0.001) over the 2-year follow-up period. ZCQ symptom severity scores improved 43% (P < 0.001) and ZCQ physical function improved 44% (P < 0.001) from pre-treatment to 2 years post-treatment. A statistically significant 50% improvement (P < 0.001) also was noted in back function. PCS and MCS each improved 40% (both P < 0.001) from pre-treatment to 2 years. Clinical success rates at 2 years were 83%-89% for ZCQ subscores, 75% for ODI, 78% for PCS, and 80% for MCS. No device infection, implant breakage, migration, or pull-out was observed, although two (3.8%) patients underwent explant with subsequent laminectomy.
CONCLUSION: Moderate LSS can be effectively treated with a minimally invasive interspinous spacer. This device is appropriate for select patients who have failed nonoperative treatment measures for LSS and meet strict anatomical criteria.

PMID: 21966217 [PubMed – in process]

Spinal intramedullary cysticercosis: a case report and literature review.

Int J Med Sci. 2011;8(5):420-3

Authors: Qi B, Ge P, Yang H, Bi C, Li Y

Neurocysticercosis, involvement of the central nervous system by taenia solium, is one of the most common parasitic diseases of the CNS. However, spinal involvement by neurocysticercosis is uncommon. Here, we reported a 40-year-old woman with intramedullary cysticercosis in the thoracic spinal cord. MRI revealed two well-defined round intramedullary lesions at T4 and T5 vertebral levels, which were homogeneously hypointense on T1WI and hyperintense on T2WI with peripheral edema. Since the patient had progressive neurological deficits, surgery was performed to decompress the spinal cord. Histopathology examination of the removed lesion proved it was intramedullary cysticercosis. In this report, we also discussed the principles of diagnosis and treatment of intramedullary cysticercosis in combination of literature review.

PMID: 21814474 [PubMed – indexed for MEDLINE]

Postlaminectomy synovial cyst formation: A possible consequence of ligamentum flavum excision.

J Clin Neurosci. 2011 Nov 1;

Authors: Walcott BP, Coumans JV

Ligamentum flavum is generally resected with impunity when a laminectomy is performed; it is a strong ligament and its removal may not be inconsequential. We sought to examine the consequence of resection of ligamentum flavum as it pertains to the formation of synovial cysts. Following IRB approval, we retrospectively reviewed the charts of consecutive patients who underwent a laminectomy for any diagnosis during the years 2009-2010. Exclusions were made for patients undergoing resection of a synovial cyst, laminectomy done as part of a fusion, and microdiscectomy. A total of 201 laminectomies were performed. 10 instances of post-laminectomy synovial cyst occurred in only the lumbar spine. Synovial cysts occurred exclusively after surgery for stenosis (n=10). Laminectomy and resection of the ligament flavum is a risk factor for the subsequent formation of a synovial cyst. Secondary synovial cyst formation should be suspected in individuals who develop radiculopathy after laminectomy for stenosis.

PMID: 22051031 [PubMed – as supplied by publisher]

Determination of minimum clinically important difference in pain, disability, and quality of life after extension of fusion for adjacent-segment disease.

J Neurosurg Spine. 2011 Sep 30;

Authors: Parker SL, Mendenhall SK, Shau D, Adogwa O, Cheng JS, Anderson WN, Devin CJ, McGirt MJ

Object Spinal surgical outcome studies rely on patient-reported outcome (PRO) measurements to assess treatment effect. A shortcoming of these questionnaires is that the extent of improvement in their numerical scores lack a direct clinical meaning. As a result, the concept of minimum clinical important difference (MCID) has been used to measure the critical threshold needed to achieve clinically relevant treatment effectiveness. As utilization of spinal fusion has increased over the past decade, so has the incidence of adjacent-segment degeneration following index lumbar fusion, which commonly requires revision laminectomy and extension of fusion. The MCID remains uninvestigated for any PROs in the setting of revision lumbar surgery for adjacent-segment disease (ASD). Methods In 50 consecutive patients undergoing revision surgery for ASD-associated back and leg pain, PRO measures of back and leg pain on a visual analog scale (BP-VAS and LP-VAS, respectively), Oswestry Disability Index (ODI), 12-Item Short Form Health Survey Physical and Mental Component Summaries (SF-12 PCS and MCS, respectively), and EuroQol-5D health survey (EQ-5D) were assessed preoperatively and 2 years postoperatively. The following 4 well-established anchor-based MCID calculation methods were used to calculate MCID: average change; minimum detectable change (MDC); change difference; and receiver operating characteristic curve (ROC) analysis for the following 2 separate anchors: health transition item (HTI) of the SF-36 and satisfaction index. Results All patients were available for 2-year PRO assessment. Two years after surgery, a statistically significant improvement was observed for all PROs (mean changes: BP-VAS score [4.80 ± 3.25], LP-VAS score [3.28 ± 3.25], ODI [10.24 ± 13.49], SF-12 PCS [8.69 ± 12.55] and MCS [8.49 ± 11.45] scores, and EQ-5D [0.38 ± 0.45]; all p < 0.001). The 4 MCID calculation methods generated a range of MCID values for each of the PROs (BP-VAS score, 2.3-6.5; LP-VAS score, 1.7-4.3; ODI, 6.8-16.9; SF-12 PCS, 6.1-12.6; SF-12 MCS, 2.4-10.8; and EQ-5D, 0.27-0.54). The area under the ROC curve was consistently greater for the HTI anchor than the satisfaction anchor, suggesting this as a more accurate anchor for MCID. Conclusions Adjacent-segment disease revision surgery-specific MCID is highly variable based on calculation technique. The MDC approach with HTI anchor appears to be most appropriate for calculation of MCID after revision lumbar fusion for ASD because it provided a threshold above the 95% CI of the unimproved cohort (greater than the measurement error), was closest to the mean change score reported by improved and satisfied patients, and was not significantly affected by choice of anchor. Based on this method, MCID following ASD revision lumbar surgery is 3.8 points for BP-VAS score, 2.4 points for LP-VAS score, 6.8 points for ODI, 8.8 points for SF-12 PCS, 9.3 points for SF-12 MCS, and 0.35 quality-adjusted life-years for EQ-5D.

PMID: 21962034 [PubMed – as supplied by publisher]

Repair of the injured human spinal cord.

J Neurosurg Spine. 2011 Sep;15(3):213-4; discussion 214-5

Authors: Fehlings MG, Wilson JR

PMID: 21663403 [PubMed – indexed for MEDLINE]

A sacral hydatid cyst mimicking an anterior sacral meningocele.

J Neurosurg Pediatr. 2011 Nov;8(5):526-9

Authors: Hemama M, Lasseini A, Rifi L, Boutarbouch M, Derraz S, Ouahabi AE, Khamlichi AE

Hydatid disease is a zoonosis caused by Echinococcus granulosus. It is a progressive disease with serious morbidity risks. Sacral hydatid disease is very uncommon, accounting for < 11% of spinal hydatidosis cases. The diagnosis of a sacral hydatid cyst is sometimes difficult because hydatidosis can simulate other cystic pathologies. The authors report on 9-year-old boy admitted to their service with a paraparesis that allowed walking without aid. The boy presented with a 2-year history of an evolving incomplete cauda equina syndrome as well as a soft cystic mass in the abdomen extending from the pelvis. Radiological examination revealed an anterior meningocele. A posterior approach with laminectomy from L-5 to S-3 was performed. Three lesions with classic features of a hydatid cyst were observed and removed. The diagnosis of hydatid cyst was confirmed histopathologically. Antihelmintic treatment with albendazole (15 mg/kg/day) was included in the postoperative treatment. The patient’s condition improved after surgery, and he recovered normal mobility. The unusual site and presentation of hydatid disease in this patient clearly supports the consideration of spinal hydatid disease in the differential diagnosis for any mass in the body, especially in endemic areas.

PMID: 22044380 [PubMed – in process]

Epidural hematoma associated with occult fracture in ankylosing spondylitis patient: a case report and review of the literature.

J Spinal Disord Tech. 2011 Oct;24(7):469-73

Authors: Elgafy H, Bransford RJ, Chapman JR

STUDY DESIGN: A case report and review of the literature.
OBJECTIVE: To highlight the risk of occult fracture associated with symptomatic epidural hematoma in patient with ankylosing spondylitis.
SUMMARY OF BACKGROUND DATA: Hyperextension injuries are common in patients with ankylosed spine. Failure of standard imaging to detect these fractures may result in delayed diagnosis. Ossification of the ligaments in these patients makes even subtle fractures grossly unstable owing to the increased lever arm. Delayed diagnosis of fractures may result in further displacement and increased risk of neurological injury.
METHODS: The clinical findings, roentgenographic appearance, and treatment were presented.
RESULTS: A 69-year-old patient with a history of ankylosing spondylitis fell 9 feet from a ladder. The patient developed pain in his neck and numbness in his hands. Initial computed tomography (CT) scan of spine showed a subtle fracture in the vertebral body of C7. A magnetic resonance imaging scan showed an epidural hematoma extending from C5 to T3. The patient was taken to the operating room urgently for decompression. Laminectomy was performed from C5 to T3 and a large epidural hematoma was evacuated. After decompression the patient had some improvement in his neurological status. A postdecompression repeat CT scan revealed obvious fracture at C6-C7 with anterior distraction indicating a hyperextension injury. The patient was taken back to the operating room within 16 hours of his decompression for C4 to T3 posterior segment instrumentation and fusion.
CONCLUSIONS: Patients with ankylosing spondylitis who sustain low-energy injuries should be considered to have a fracture especially if they develop epidural hematoma. A high index of suspicion is necessary in such a case. Imaging studies including magnetic resonance imaging and CT scans should be reviewed carefully to rule out any occult fracture.

PMID: 21945925 [PubMed – in process]

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