The lumbar backbone age-related degenerative illness influences the BMD not the TBS: the Osteolaus cohort.
Osteoporos Int. 2017 Mar;28(three):909-915
Authors: Padlina I, Gonzalez-Rodriguez E, Hans D, Metzger M, Stoll D, Aubry-Rozier B, Lamy O
We evaluated the affect of degenerative illness and fractured vertebra on lumbar backbone bone mineral density (BMD) and trabecular bone rating (TBS) in 1500 ladies aged 50-80 years. TBS was not affected by a degenerative illness. Whereas BMD will increase after 62.5 years, TBS continues to say no. TBS ought to play a number one position in lumbar backbone analysis.
INTRODUCTION: After menopause, lumbar backbone (LS) BMD and TBS values lower. Degenerative illness (DD) will increase with age and have an effect on LS BMD. The purpose of this examine was to measure modifications in LS BMD and TBS in ladies 50 to 80 years outdated, considering the influence of fractured vertebrae and DD.
METHODS: LS BMD, TBS, and vertebral fracture evaluation had been evaluated within the OsteoLaus cohort (1500 ladies, 50-80 years outdated). The exams had been analyzed following ISCD pointers to determine vertebrae with fractures or DD (Vex).
RESULTS: 1443 ladies had been enrolled: imply age 66.7 ± 11.7 years, BMI 25.7 ± four.four. LS BMD and TBS had been weakly correlated (r2 = Zero.16). The correlation (Vex excluded) between age and BMD was +Zero.03, between age and TBS -Zero.34. In accordance with age group, LS BMD was 1.2 to three.2% larger earlier than excluding Vex (p < Zero.001). TBS had an insignificant change of <1% after excluding Vex. LS BMD (Vex) decreased by four.6% between 52.5 and 62.5 years, and elevated by 2.6% between 62.5 and 77.5 years. TBS (Vex excluded) values decreased steadily with age with an general lack of eight.99% between 52.5 and 77.5 years. Backbone TBS, femoral neck, and whole hip BMD regularly decreased with age, reaching one SD between the oldest and youngest group.
CONCLUSIONS: TBS just isn’t affected by DD. Whereas BMD will increase after 62.5 years, TBS continues to say no. For lumbar backbone analysis, in view of its independence from DD, TBS ought to play a number one position within the prognosis in complement to BMD.
PMID: 27900426 [PubMed – indexed for MEDLINE]