The affect of synthetic nucleus pulposus substitute on stress distribution within the cartilaginous endplate in a three-dimensional finite ingredient mannequin of the lumbar intervertebral disc.
Drugs (Baltimore). 2017 Dec;96(50):e9149
Authors: Wang Y, Yi XD, Li CD
OBJECTIVE: This examine aimed to research the consequences concerned with the substitute nucleus pulposus (NP) substitute on stress distribution of the cartilaginous endplate (CEP) in a three-dimensional lumbar intervertebral disc (IVD) mannequin utilizing a finite ingredient (FE) evaluation.
METHODS: A wholesome male volunteer was recruited for the needs of the examine and a spiral computed tomography scan was subsequently performed to acquire the info data in relation to the L4/5 movement phase. An FE mannequin of the L4/5 movement phase constructed, on the premise of which degenerative IVD, IVD with NP elimination, and IVD with NP substitute have been in flip constructed. The stress distribution of the CEP and bulging of IVD have been estimated utilizing numerous movement states, together with axial loading, ahead flexion, backward extension, left axial rotation, and proper axial rotation.
RESULTS: Beneath totally different movement states, the vertebral stress was greater within the degenerative IVD, the IVD with NP elimination, and the IVD with NP substitute, compared to that of the traditional IVD. Moreover, the next vertebral stress was detected within the degenerative IVD than the IVD with NP elimination and the IVD with NP substitute. An excellent distribution of vertebral stress was noticed within the IVD mannequin with a synthetic NP substitute, whereas the vertebral stress and bulging displacement have been decrease than after NP elimination. Our findings offered affirmation that stress of the CEP was per the vertebral stress.
CONCLUSION: This examine offered proof suggesting that NP substitute, vertebral stress, and bulging displacement are decrease than that of degenerative IVD and IVD with NP elimination underneath totally different movement states.
PMID: 29390319 [PubMed – indexed for MEDLINE]