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The central nervous system solitary fibrous tumor: a review of clinical, imaging and pathologic findings among all reported cases from 1996 to 2010

OBJECTIVE: Central nervous system (CNS) solitary fibrous tumor (SFT) is a rare lesion first identified as a unique entity in 1996. We describe two cases treated at the University of Florida followed by a review of all reported cases of CNS SFT between 1996 and 2010. METHODS: A review of the literature was performed to identify all reported cases of CNS SFT. RESULTS: 189 cases (including the two presented herein) were discovered, of which 46 were spinal and 143 were intracranial. Demographic, imaging, and pathologic findings are presented. Roughly 6% of reported lesions are malignant. Subtotal resection (STR) was associated with a 16-fold increased odds of recurrence (OR 15.9, 95% CI 5.5-46.1), although mean follow-up was shorter in those cases of GTR without recurrence. CONCLUSION: CNS SFT is a rare lesion. Six percent of lesions are malignant. GTR is superior to STR although the degree of superiority is not clear

Keywords : Adult,Age Factors,Brain Neoplasms,Central Nervous System,Central Nervous System Neoplasms,Cerebral Angiography,epidemiology,etiology,Female,Florida,Humans,Magnetic Resonance Imaging,Male,methods,Middle Aged,Neoplasm Recurrence,Local,Nervous System,Neurosurgery,Neurosurgical Procedures,pathology,Quadriplegia,Recurrence,Solitary Fibrous Tumors,Spinal Cord Neoplasms,surgery,Treatment Outcome,Universities,, Central,Nervous,System,Solitary,Fibrous, what is pars defect

Date of Publication : 2011 Nov

Authors : Fargen KM;Opalach KJ;Wakefield D;Jacob RP;Yachnis AT;Lister JR;

Organisation : Department of Neurosurgery, University of Florida College of Medicine, Gainesville, FL, USA. kyle.fargen@neurosurgery.ufl.edu

Journal of Publication : Clin Neurol Neurosurg

Pubmed Link : https://www.ncbi.nlm.nih.gov/pubmed/21872387

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