OBJECTIVE: Late neurologic deterioration after brachial plexus injury (BPI) is uncommon and may be caused by multiple etiologies. An unusual, previously unreported, case of late neurologic deterioration after BPI is presented. METHODS: A pediatric patient previously treated for a traumatic preganglionic BPI and presenting with neurologic deterioration 5 years after his injury is reviewed. RESULTS: Magnetic resonance imaging and computed tomography myelogram revealed spinal cord herniation at the same level of the previous nerve root avulsions. Surgical open biopsy demonstrated a spinal cord anaplastic astrocytoma. Despite craniospinal radiotherapy and different regimens of chemotherapy, he died 4 years later from leptomeningeal spread. CONCLUSION: This case illustrates a previously unreported cause of late neurologic deterioration following BPI. The probable coincidental versus possible causal interrelationship of these two processes (BPI and spinal cord tumor) is discussed, but no conclusions can be reached
Keywords : analogs & derivatives,Antineoplastic Agents,Antineoplastic Agents,Alkylating,Astrocytoma,Biopsy,Brachial Plexus,Child,Combined Modality Therapy,complications,Dacarbazine,diagnosis,etiology,Fatal Outcome,Horner Syndrome,Humans,injuries,Laminectomy,Magnetic Resonance Imaging,Male,Meningocele,methods,Muscle Weakness,Neurosurgical Procedures,Off-Road Motor Vehicles,pathology,radiotherapy,Reconstructive Surgical Procedures,Spinal Cord,Spinal Cord Neoplasms,Spine,surgery,Temozolomide,therapeutic use,therapy,, Spinal,Cord,Tumor,Following,Avulsive, london ontario laser clinic
Date of Publication : 2010 Aug
Authors : Hebert-Blouin MN;Bishop AT;Shin AY;Wetmore C;Spinner RJ;
Organisation : Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota, USA
Journal of Publication : World Neurosurg
Pubmed Link : https://www.ncbi.nlm.nih.gov/pubmed/21492572
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