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Step on the accelerator: modern treatment of constipation – Lumbar Fusion

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This article discusses the effective management of constipation, the challenges in making a positive diagnosis, and the importance of a positive patient-provider relationship. It highlights recent findings such as the high percentage of patients with severe constipation and upper gastrointestinal symptoms, the effectiveness of gold kiwifruits in treating constipation, and the high rate of opioid use after lumbar fusion surgery. The article also mentions the dissatisfaction of patients with over-the-counter treatments and explores pharmacologic and nonpharmacologic treatments for constipation. Overall, constipation significantly impacts patients’ quality of life, and both pharmacologic and nonpharmacologic treatments show promise in improving symptoms and quality of life

Summarised by Mr Mo Akmal – Lead Spinal Surgeon
The London Spine Unit : innovative spine clinic in UK

Published article

PURPOSE OF REVIEW: This review aims to explore effective management of constipation, examine challenges in making a positive diagnosis, and highlights the significance of a positive patient-provider relationship and emerging treatments.

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Curr Opin Gastroenterol. 2023 Sep 4. doi: 10.1097/MOG.0000000000000982. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: This review aims to explore effective management of constipation, examine challenges in making a positive diagnosis, and highlights the significance of a positive patient-provider relationship and emerging treatments.RECENT FINDINGS: Less than one-fifth of patients feel satisfied with treatment of their constipation.,

Curr Opin Gastroenterol. 2023 Sep 4. doi: 10.1097/MOG.0000000000000982. Online ahead of print.

ABSTRACT

PURPOSE OF REVIEW: This review aims to explore effective management of constipation, examine challenges in making a positive diagnosis, and highlights the significance of a positive patient-provider relationship and emerging treatments.

RECENT FINDINGS: Less than one-fifth of patients feel satisfied with treatment of their constipation. Sixty percent of patients with functional dyspepsia and gastroparesis have severe to very severe constipation that correlates with their upper gastrointestinal symptom severity. Two gold kiwifruits are noninferior to 10 g of psyllium in the treatment of constipation. More than 40% of patients undergoing lumbar fusion continue to fill opioid prescriptions 90 days after surgery, contributing to 80 000 chronic opioid users annually. Most patients are using over-the-counter (OTC) treatments for constipation with greater than 60% dissatisfied. Pharmacologic management involves the use of GCC agonists and emerging drug classes such as bile acid transport inhibitors and sodium hydrogen exchanger isoform 3 (NHE3) inhibitors. Nonpharmacologic treatments, including neuromodulation and FDA-approved vibrating capsule, show promise in improving symptoms and quality of life.

SUMMARY: Constipation significantly impacts patients’ quality of life and well being and the majority of patients are refractory to conservative measures and OTC treatments. Both pharmacologic and nonpharmacologic treatments hold promise for improving constipation and quality of life.

PMID:37678175 | DOI:10.1097/MOG.0000000000000982

The London Spine Unit : innovative spine clinic in UK

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Step on the accelerator: modern treatment of constipation

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Curr Opin Gastroenterol. 2023 Sep 4. doi: 10.1097/MOG.0000000000000982. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: This review aims to explore effective management of constipation, examine challenges in making a positive diagnosis, and highlights the significance of a positive patient-provider relationship and emerging treatments.RECENT FINDINGS: Less than one-fifth of patients feel satisfied with treatment of their constipation.

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