Menu
Menu
19 Harley St, London, W1G 9QJ, UK
We are London's Top Spine Clinic

Staphylococcus-Related Glomerulonephritis Mimicking Henoch-Schönlein Purpura and Cryoglobulinemic Vasculitis in a Affected person With an Epidural Abscess: A Case Report and Temporary Assessment of the Literature.

Related Articles

Staphylococcus-Related Glomerulonephritis Mimicking Henoch-Schönlein Purpura and Cryoglobulinemic Vasculitis in a Affected person With an Epidural Abscess: A Case Report and Temporary Assessment of the Literature.

Can J Kidney Well being Dis. 2018;5:2054358118776325

Authors: Mahmood T, Puckrin R, Sugar L, Naimark D

Summary
Rationale: Staphylococcus-associated glomerulonephritis (SAGN) is a uncommon immune complex-mediated glomerulonephritis related to lively Staphylococcus an infection. We report a case illustrating the significance of medical historical past and kidney biopsy findings in establishing the proper analysis.
Presenting considerations of the affected person: We report the case of a 64-year-old man with alcohol-associated cirrhosis, sort 2 diabetes mellitus, and hypertension who introduced to hospital with decrease again and belly ache, rectal bleeding, a purpuric decrease extremity rash, and oliguric acute kidney damage with microscopic hematuria and nephrotic-range proteinuria.
Diagnoses: Pores and skin biopsy revealed IgA leukocytoclastic vasculitis. Serum cryoglobulins have been constructive and there was hypocomplementemia with a low C3 stage. Magnetic resonance imaging of the lumbar backbone revealed septic discitis and epidural abscesses brought on by a latest Staphylococcus aureus bacteremia. Kidney biopsy confirmed IgA-dominant and C3-dominant proliferative glomerulonephritis with subepithelial humps in line with SAGN.
Interventions: Pressing hemodialysis was initiated together with a protracted course of intravenous cefazolin.
Outcomes: Remarkably, the affected person demonstrated a whole restoration of renal operate after 2 months of dialysis dependence and profitable therapy of the epidural abscesses.
Classes discovered: This case exhibits that SAGN can intently mimic the medical, laboratory, and histological presentation of Henoch-Schönlein Purpura or cryoglobulinemic vasculitis. Scientific historical past and kidney biopsy, significantly electron microscopic evaluation, are important to establishing the proper analysis to keep away from the pointless and doubtlessly dangerous administration of immunosuppression. Regardless of the usually poor prognosis of SAGN, this case report illustrates that full renal restoration stays doable with supportive care and eradication of the underlying an infection.

PMID: 29900000 [PubMed]

Share to care...

Share on facebook
Facebook
Share on twitter
Twitter
Share on pinterest
Pinterest
Share on google
Google+
Share on linkedin
LinkedIn
Share on skype
Skype

What we do...

The Harley Street Hospital

Testimonials

What is London spine unit and How it Works

The London Spine Unit was established in 2005 and has successfully treated over 5000 patients. All conditions are treated.

We treat all spinal disorders

The London Spine Unit specialises in Minimally Invasive Treatments allowing rapid recovery and return to normal function

Trusted by patients worldwide

The London Spine Unit provides the highest quality care to all patients and has VIP services for those seeking exceptional services

What our patients say about us ......

Spine Fracture patient

Very good procedure and treatment. Thank you. J.L. You May Also Like:Patient with intermittent back painL5 Nerve Root CompressionPatient suffering from severe disc degenerationInjections for

Read More »