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Selective Arterial Embolization for the Therapy of Sacral and Pelvic Large Cell Tumor: A Systematic Assessment.

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Selective Arterial Embolization for the Therapy of Sacral and Pelvic Large Cell Tumor: A Systematic Assessment.

Orthop Surg. 2017 Might;9(2):139-144

Authors: He SH, Xu W, Solar ZW, Liu WB, Liu YJ, Wei HF, Xiao JR

Summary
Large cell tumor of the bone (GCTB) is a regionally aggressive tumor with a sure distant metastatic charge. For sacral GCT (SGCT) and pelvic GCT (PGCT), surgical procedure has its limitations, particularly for unresectable or recurrent tumors. Selective arterial embolization (SAE) is reported to be an possibility for therapy in a number of instances, however there are few systematic opinions on the results of SAE on SGCT and/or PGCT. Medline and Embase databases have been looked for eligible English articles. Inclusion and exclusion standards have been carried out earlier than looking. All of the medical components have been measured by SPSS software program, with P-values ?zero.05 thought-about statistically vital. A complete of 9 articles have been retrieved, together with 44 sufferers receiving SAE starting from 1 to 10 instances. Through the imply follow-up interval of 85.eight months, the radiographic response charge was 81.eight%, with a neighborhood management and general survival charge of 75% and 81.eight%, respectively. No bowel, bladder, or sexual dysfunction was noticed. Three sufferers developed distant metastases and at last died. Sufferers with major tumors tended to have higher prognosis than these with recurrence (P = zero.039). The favorable outcomes of SAE counsel that it might be another therapy for SGCT and PGCT sufferers for whom surgical procedure will not be applicable.

PMID: 28644557 [PubMed – indexed for MEDLINE]

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