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Safety and Clinical Results of Continuous Low-Dose Aspirin in Microendoscopic Laminectomy – Lumbar Spinal Stenosis

This article discusses a study that aimed to evaluate the safety of continuing oral low-dose aspirin (LDA) during the perioperative period in microendoscopic laminectomy (MEL), a type of spinal surgery. The study included 88 patients who underwent MEL for lumbar spinal canal stenosis. The patients were classified into three groups: Group A (did not undergo anticoagulation therapy), Group B (stopped anticoagulation therapy perioperatively), and Group C (continued LDA throughout the perioperative period). The study assessed various factors such as surgery time, blood loss, perioperative complications, clinical outcomes, and the presence of hematoma and dural sac on MRI. The results showed that there were no significant differences between the three groups in terms of these factors. Therefore, the study suggests that it might be possible to continue the oral administration of LDA during the perioperative period in MEL without adverse effects on complications and outcomes

Summarised by Mr Mo Akmal – Lead Spinal Surgeon
The London Spine Unit : innovative spinal clinic in UK

Published article

CONCLUSIONS: The continuation of LDA throughout the perioperative periods did not affect perioperative complications and clinical outcomes of one-level MEL. In MEL, it might be possible to continue oral administration of LDA throughout the perioperative periods.

Lumbar Decompression Surgery Expert. Best Spinal Surgeon UK
Spine Surg Relat Res. 2023 Jan 12;7(4):350-355. doi: 10.22603/ssrr.2022-0224. eCollection 2023 Jul 27.ABSTRACTINTRODUCTION: It remains controversial whether it is better to continue oral low-dose aspirin (LDA) during the perioperative period in spinal surgery. This study aims to evaluate the safety of continued LDA administration in the perioperative periods of microendoscopic laminectomy (MEL) by assessing perioperative,

Spine Surg Relat Res. 2023 Jan 12;7(4):350-355. doi: 10.22603/ssrr.2022-0224. eCollection 2023 Jul 27.

ABSTRACT

INTRODUCTION: It remains controversial whether it is better to continue oral low-dose aspirin (LDA) during the perioperative period in spinal surgery. This study aims to evaluate the safety of continued LDA administration in the perioperative periods of microendoscopic laminectomy (MEL) by assessing perioperative complications and clinical outcomes.

METHODS: We ultimately included 88 patients (35 males, 53 females) who underwent one level of MEL for lumbar spinal canal stenosis from April 2016 to March 2022. Patients who did not undergo anticoagulation therapy were classified into Group A (65 patients), those who stopped anticoagulation therapy at the perioperative periods were classified into Group B (9 patients), and those who continued oral administration of LDA throughout the perioperative periods were classified into Group C (14 patients). Surgery time, intraoperative estimate blood loss (EBL), differences between hemoglobin (Hb) and platelet (Plt) before and after surgery, perioperative complications, and cross-sectional area of hematoma and dural sac on MRI taken within 1 week and at 6 months or more after surgery were assessed between three groups. The EuroQol-5 dimensions (EQ-5D), Oswestry Disability Index (ODI), and Japanese Orthopaedic Association Back Pain Evaluation Questionnaire (JOABPEQ) were also evaluated as the clinical outcomes.

RESULTS: There was no statistically significant difference between the three groups in operation time, intraoperative EBL, differences between Hb and Plt before and after surgery, and cross-sectional area of hematoma and dural sac on MRI. A case of hematoma removal was confirmed in Group A. There was also no statistically significant difference between the three groups in EQ-5D, ODI, and each domain of JOABPEQ.

CONCLUSIONS: The continuation of LDA throughout the perioperative periods did not affect perioperative complications and clinical outcomes of one-level MEL. In MEL, it might be possible to continue oral administration of LDA throughout the perioperative periods.

PMID:37636142 | PMC:PMC10447200 | DOI:10.22603/ssrr.2022-0224

The London Spine Unit : innovative spinal clinic in UK

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Safety and Clinical Results of Continuous Low-Dose Aspirin in Microendoscopic Laminectomy

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Spine Surg Relat Res. 2023 Jan 12;7(4):350-355. doi: 10.22603/ssrr.2022-0224. eCollection 2023 Jul 27.ABSTRACTINTRODUCTION: It remains controversial whether it is better to continue oral low-dose aspirin (LDA) during the perioperative period in spinal surgery. This study aims to evaluate the safety of continued LDA administration in the perioperative periods of microendoscopic laminectomy (MEL) by assessing perioperative

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