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Role of Pre-Operative Nutrition Status on Surgical Site Infection After Posterior Lumbar Interbody Fusion: A Retrospective Study – Lumbar Fusion

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This article is a retrospective case-control study that aimed to determine the role of pre-operative systemic and local nutritional factors on patients developing a surgical site infection (SSI) after posterior lumbar interbody fusion (PLIF) surgery. The study collected data from a cohort of 766 adult patients who underwent PLIF surgery. The results showed that lower pre-operative prognostic nutritional index (PNI) and higher relative fat thickness were independently associated with the development of deep SSI after PLIF surgery. These findings highlight the importance of considering pre-operative nutritional status as a risk factor for SSI in PLIF patients

Summarised by Mr Mo Akmal – Lead Spinal Surgeon
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Published article

Background: A retrospective case-control study to determine the role of pre-operative systemic and local nutritional factors on patients developing a surgical site infection (SSI) after posterior lumbar interbody fusion (PLIF). Surgical site infection after PLIF remains a substantial cause of morbidity. The literature demonstrates the prognosis of surgical patients is associated with pre-operative nutritional status that not only includes systemic nutritional factors, such as prognostic…

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Surg Infect (Larchmt). 2023 Nov 28. doi: 10.1089/sur.2023.051. Online ahead of print.ABSTRACTBackground: A retrospective case-control study to determine the role of pre-operative systemic and local nutritional factors on patients developing a surgical site infection (SSI) after posterior lumbar interbody fusion (PLIF). Surgical site infection after PLIF remains a substantial cause of morbidity. The literature demonstrates,

Surg Infect (Larchmt). 2023 Nov 28. doi: 10.1089/sur.2023.051. Online ahead of print.

ABSTRACT

Background: A retrospective case-control study to determine the role of pre-operative systemic and local nutritional factors on patients developing a surgical site infection (SSI) after posterior lumbar interbody fusion (PLIF). Surgical site infection after PLIF remains a substantial cause of morbidity. The literature demonstrates the prognosis of surgical patients is associated with pre-operative nutritional status that not only includes systemic nutritional factors, such as prognostic nutritional index (PNI), body mass index (BMI), and serum albumin, but also local nutritional factors, such as subcutaneous fat thickness at the surgical site, including absolute fat thickness and relative fat thickness. However, the role of pre-operative nutrition status in SSI after PLIF surgery remains unclear. Patients and Method: A retrospective review was performed on a consecutive cohort of 766 consecutive adult patients who underwent PLIF surgery for lumbar degenerative conditions between 2020 and 2021 at Second Xiangya Hospital. Previously identified risk factors as well as systemic and local nutritional factors nutritional factors were collected. Results: Among the 766 patients, 38 had post-operative SSI including 15 superficial SSI and 23 deep SSI. Univariable analysis showed that body weight, BMI, PNI, serum albumin, and relative fat thickness differed between the SSI and non-SSI groups. Multivariable logistic regression analysis showed that pre-operative PNI and relative fat thickness were independently associated with SSI after PLIF surgery. s: Lower pre-operative PNI and higher relative fat thickness are independent risk factors for developing deep SSI after PLIF.

PMID:38016129 | DOI:10.1089/sur.2023.051

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Role of Pre-Operative Nutrition Status on Surgical Site Infection After Posterior Lumbar Interbody Fusion: A Retrospective Study

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Surg Infect (Larchmt). 2023 Nov 28. doi: 10.1089/sur.2023.051. Online ahead of print.ABSTRACTBackground: A retrospective case-control study to determine the role of pre-operative systemic and local nutritional factors on patients developing a surgical site infection (SSI) after posterior lumbar interbody fusion (PLIF). Surgical site infection after PLIF remains a substantial cause of morbidity. The literature demonstrates

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