Function of disc space and trabecular bone density on lumbar spinal column fracture danger curves beneath vertical impression.
J Biomech. 2018 Mar 02;:
Authors: Yoganandan N, Moore J, Pintar FA, Banerjee A, DeVogel N, Zhang J
Whereas research have been performed utilizing human cadaver lumbar spines to know harm biomechanics when it comes to stability/power to fracture, and physiological responses beneath pure-moment/follower hundreds, knowledge are sparse for inferior-to-superior impacts. Accidents happen beneath this mode from underbody blasts.
OBJECTIVES: decide position of age, disc space, and trabecular bone density on tolerances/danger curves beneath vertical loading from a managed group of specimens. T12-S1 columns had been obtained, pretest X-rays and CTs taken, load cells connected to each ends, impacts utilized at S1-end utilizing customized vertical accelerator machine, and posttest X-ray, CT, and dissections achieved. BMD of L2-L4 vertebrae had been obtained from QCT. Survival analysis-based Human Damage Chance Curves (HIPCs) had been derived utilizing proximal and distal forces. Age, space, and BMD had been covariates. Forces had been thought-about uncensored, representing the load carrying capability. The Akaike Info Criterion was used to find out optimum distributions. The imply forces, ±95% confidence intervals, and Normalized Confidence Interval Dimension (NCIS) had been computed. The Lognormal distribution was the optimum perform for each forces. Age, space, and BMD weren’t important (p?>?zero.05) covariates for distal forces, whereas solely BMD was important for proximal forces. The NCIS was the bottom for force-BMD covariate HIPC. The HIPCs for each genders at 35 and 45?years had been based mostly on inhabitants BMDs. These HIPCs function human tolerance standards for automotive, navy, and different functions. On this managed group of samples, BMD is a greater predictor-covariate that characterizes lumbar column harm beneath inferior-to-superior impacts.
PMID: 29559244 [PubMed – as supplied by publisher]