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Risk factors of cage subsidence following oblique lumbar interbody fusion: a meta-analysis and systematic review – Lumbar Fusion

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The article is a systematic review that aims to evaluate the risk factors for cage subsidence (CS) after oblique lumbar interbody fusion (OLIF). The researchers searched for cohort and case-control studies reporting potential risk factors for CS following OLIF in medical databases. They identified 8 studies with 280 cases of CS from 832 patients that met the inclusion criteria. The results showed that elderly patients over 60 years old, osteoporosis, end plate injury, and over-distraction of intervertebral space were potential risk factors for CS, while the hounsfield units (HU) value of the vertebral body was a protective factor. The number of operative segments did not increase the risk of CS. The authors concluded that effective preventive measures should be implemented based on these risk factors

Summarised by Mr Mo Akmal – Lead Spinal Surgeon
The London Spine Unit : most established treatment hospital in UK

Published article

S: Older, osteoporosis, endplate injury and over-distraction of the intervertebral space may increase the risk of CS after OLIF. Although the incidence rate of CS is low, implementing effective preventions is a priority for clinicians based on the above risk factors.

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World Neurosurg. 2023 Dec 23:S1878-8750(23)01844-2. doi: 10.1016/j.wneu.2023.12.110. Online ahead of print.ABSTRACTSTUDY DESIGN: Systematic review OBJECTIVES: The aim of this study was to evaluate the risk factors for cage subsidence (CS) after oblique lumbar interbody fusion (OLIF).METHODS: The cohort and case-control studies which reporting potential risk factors for CS following OLIF were searched in PubMed, Embase,

World Neurosurg. 2023 Dec 23:S1878-8750(23)01844-2. doi: 10.1016/j.wneu.2023.12.110. Online ahead of print.

ABSTRACT

STUDY DESIGN: Systematic review OBJECTIVES: The aim of this study was to evaluate the risk factors for cage subsidence (CS) after oblique lumbar interbody fusion (OLIF).

METHODS: The cohort and case-control studies which reporting potential risk factors for CS following OLIF were searched in PubMed, Embase and Web of Science from database inception to June 17, 2023. Two researchers independently screened the literature, extracted data, and evaluated the quality of the literature according to Newcastle-Ottawa scale (Newcastle-Ottawa Scale, NOS), the RevMan5.3 software was used for Meta analysis. χ2 statistics and I2 statistics were used to evaluate heterogeneity, and the analysis results were represented by forest plots.

RESULTS: A total of 8 studies with 280 cases of CS from 832 patients underwent OLIF met the inclusion criteria. Elderly patients over 60 years old(OR=2.44, 95%CI 1.38∼4.31, P=0.002), osteoporosis (OR=4.18, 95%CI 2.30∼7.61, P=0.002), end plate injury (OR=5.72, 95%CI 2.32∼14.11, P=0.0002), and over-distraction of intervertebral space (OR=1.67, 95%CI 1.3 2-2.11 P<0.0001) were potential risk factors, while hounsfield units(HU) value of the vertebral body (OR=0.97, 95%CI 0.95∼1.00, P=0.02) is a protective factor. The number of operative segments did not increase the risk of CS.

S: Older, osteoporosis, endplate injury and over-distraction of the intervertebral space may increase the risk of CS after OLIF. Although the incidence rate of CS is low, implementing effective preventions is a priority for clinicians based on the above risk factors.

PMID:38145652 | DOI:10.1016/j.wneu.2023.12.110

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Risk factors of cage subsidence following oblique lumbar interbody fusion: a meta-analysis and systematic review

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World Neurosurg. 2023 Dec 23:S1878-8750(23)01844-2. doi: 10.1016/j.wneu.2023.12.110. Online ahead of print.ABSTRACTSTUDY DESIGN: Systematic review OBJECTIVES: The aim of this study was to evaluate the risk factors for cage subsidence (CS) after oblique lumbar interbody fusion (OLIF).METHODS: The cohort and case-control studies which reporting potential risk factors for CS following OLIF were searched in PubMed, Embase

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