Danger Elements for Cement Loosening after Vertebroplasty for Osteoporotic Vertebral Fracture with Intravertebral Cleft: A Retrospective Evaluation.
Asian Backbone J. 2018 Oct;12(5):935-942
Authors: Nakamae T, Yamada Okay, Tsuchida Y, Osti OL, Adachi N, Fujimoto Y
STUDY DESIGN: Retrospective case-control research.
PURPOSE: To judge the first outcomes and radiographic outcomes of percutaneous vertebroplasty (PVP) in sufferers with singlelevel osteoporotic vertebral fracture (OVF) with intravertebral cleft (IVC) to establish the chance components for cement loosening after PVP.
OVERVIEW OF LITERATURE: PVP is a broadly accepted technique for managing painful OVF; nonetheless, cement loosening often happens with poor outcomes.
METHODS: This retrospective research concerned 195 sufferers handled with PVP for single-level OVF with IVC. Six months thereafter, the first outcomes have been evaluated utilizing the Visible Analog Scale (VAS) for again ache and the modified Oswestry Incapacity Index. Computed tomography was performed to detect cement loosening. Doable threat components, resembling age, intercourse, wedging angle, intravertebral instability, Parkinson’s illness, spinous course of fracture, ankylosing spinal hyperostosis, cut up vertebrae, and adjoining intervertebral vacuum, have been assessed.
RESULTS: Forty-nine sufferers (25%) skilled cement loosening 6 months after PVP. The imply VAS scores have been considerably greater in sufferers with cement loosening than in these with out (50 vs. 26 mm, respectively; p <zero.01). Cement loosening was carefully related to intravertebral instability (odds ratio [OR], 1.20; 95% confidence interval [CI], 1.04-1.40; p =zero.015), Parkinson’s illness (OR, 54.31; 95% CI, four.47-659.53; p =zero.zero02), spinous course of fracture (OR, 7.11; 95% CI, 1.65-30.60; p =zero.009), and cut up vertebrae (OR, 11.59; 95% CI, 1.64-82.02; p =zero.014).
CONCLUSIONS: Sufferers with cement loosening skilled worse again ache than these with out cement loosening. The vital threat components that influenced cement loosening after PVP have been excessive intravertebral instability, Parkinson’s illness, spinous course of fracture, and cut up vertebrae.
PMID: 30213178 [PubMed]