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Research progress on the influence of Modic changes on lumbar interbody fusion and its treatment measure – Lumbar Fusion

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The article titled “Research Progress of Modic Changes and its Influence on Lumbar Interbody Fusion” reviews the current research on Modic changes and their impact on lumbar interbody fusion. The study extensively examines domestic and foreign literature related to Modic changes and discusses the etiology of these changes. It identifies various factors that may contribute to the development of Modic changes, such as mechanical factors, autoimmune factors, low toxic infection factors, and genetic factors. The article also highlights how Modic changes can lead to fusion failure and cage subsidence after lumbar interbody fusion. The authors suggest that preoperative evaluation, careful surgical techniques, management of osteoporosis, and appropriate cage selection can help prevent or reduce the risk of fusion failure or cage subsidence. Overall, the active perioperative intervention of Modic changes can improve clinical outcomes for patients undergoing lumbar interbody fusion

Summarised by Mr Mo Akmal – Lead Spinal Surgeon
The London Spine Unit : top treatment clinic in the world

Published article

CONCLUSION: Modic changes may lead to fusion failure and cage subsidence after lumbar interbody fusion, and active perioperative intervention of Modic changes is helpful to improve the clinical prognosis.

Lumbar Fusion Surgery Expert. Best Spinal Surgeon UK
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2023 Aug 15;37(8):1026-1030. doi: 10.7507/1002-1892.202302007.ABSTRACTOBJECTIVE: To review the research progress of Modic changes and its influence on lumbar interbody fusion.METHODS: The domestic and foreign literature related to Modic changes and its influence on lumbar interbody fusion was extensively reviewed. The etiology of Modic changes was summarized,

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2023 Aug 15;37(8):1026-1030. doi: 10.7507/1002-1892.202302007.

ABSTRACT

OBJECTIVE: To review the research progress of Modic changes and its influence on lumbar interbody fusion.

METHODS: The domestic and foreign literature related to Modic changes and its influence on lumbar interbody fusion was extensively reviewed. The etiology of Modic changes was summarized, and the treatment measures of Modic changes on lumbar interbody fusion were discussed.

RESULTS: The etiology of Modic changes is not clear, which may be related to mechanical factors, autoimmune factors, low toxic infection factors, and genetic factors. Modic changes may lead to fusion failure and cage subsidence after lumbar interbody fusion. Preoperative evaluation of endplate sclerosis, reduction of iatrogenic endplate injury, fine operating of intervertebral space, management of osteoporosis, and selection of appropriate cage can prevent or reduce fusion failure or cage subsidence.

CONCLUSION: Modic changes may lead to fusion failure and cage subsidence after lumbar interbody fusion, and active perioperative intervention of Modic changes is helpful to improve the clinical prognosis.

PMID:37586805 | DOI:10.7507/1002-1892.202302007

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Research progress on the influence of Modic changes on lumbar interbody fusion and its treatment measure

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Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2023 Aug 15;37(8):1026-1030. doi: 10.7507/1002-1892.202302007.ABSTRACTOBJECTIVE: To review the research progress of Modic changes and its influence on lumbar interbody fusion.METHODS: The domestic and foreign literature related to Modic changes and its influence on lumbar interbody fusion was extensively reviewed. The etiology of Modic changes was summarized

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