Quantitative scientific outcomes of remedy for head and neck lymphedema.
Adv Radiat Oncol. 2018 Jul-Sep;Three(Three):366-371
Authors: Doke KN, Bowman L, Shnayder Y, Shen X, TenNapel M, Thomas SM, Neupane P, Yeh HW, Lominska CE
Goal: Head and neck surgical procedure and radiation trigger tissue fibrosis that results in useful limitations and lymphedema. The target of this examine was to find out whether or not lymphedema remedy after surgical procedure and radiation for head and neck most cancers decreases neck circumference, will increase cervical vary of movement, and improves ache scores.
Strategies and supplies: A retrospective evaluate of all sufferers with squamous cell carcinoma of the oral cavity, oropharynx, or larynx who have been handled with high-dose radiation remedy at a single heart between 2011 and 2012 was carried out. Sufferers acquired definitive or postoperative radiation for squamous cell carcinoma of the oral cavity, oropharynx, or larynx. Sufferers have been referred to a single, licensed, lymphedema therapist with specialty coaching in head and neck most cancers after completion of radiation therapy and therapeutic of acute toxicity (usually 1-Three months). Sufferers underwent at the very least Three months of handbook lymphatic decongestion and expert fibrotic methods. Circumferential neck measurements and cervical vary of movement have been measured clinically at 1, Three, 6, 9, and 12 months after completion of radiation remedy. Ache scores have been additionally recorded.
Outcomes: Thirty-four consecutive sufferers have been eligible and underwent a median of 6 months of lymphedema remedy (Vary, Three-12 months). Clinically measured whole neck circumference decreased in all sufferers with 1 month of therapy. Cervical rotation elevated by 30.2% on the left and 27.9% on the precise at 1 month and continued to enhance as much as 44.6% and 55.Three%, respectively, at 12 months. Sufferers present process remedy had improved ache scores from four.Three at baseline to 2.zero after 1 month.
Conclusions: Lymphedema remedy is related to goal enhancements in vary of movement, neck circumference, and ache scores within the majority of sufferers.
PMID: 30202804 [PubMed]