Propionibacterium acnes infections in sufferers with idiopathic scoliosis: a case-control research and evaluation of the literature.
J Baby Orthop. 2018 Apr 01;12(2):173-180
Authors: Swarup I, Gruskay J, Worth M, Yang J, Blanco J, Perlman S, Widmann R
Goal: Surgical website an infection (SSI) brought on by Propionibacterium acnes is an rare however devastating complication after spinal fusion. The aim of this research was to determine danger components for SSI with Propionibacterium acnes after spinal fusion for juvenile and adolescent idiopathic scoliosis (JIS and AIS).
Strategies: A case-control research was carried out. Every case was matched 2:1 for age, gender and analysis. Retrospective chart evaluation was carried out to acquire related demographic, surgical and medical knowledge for all instances and controls. Statistical evaluation included paired t-test and McNemar take a look at, in addition to actual logistic regression and strong regression fashions.
Outcomes: This research included ten an infection instances (eight AIS, two JIS) and 20 controls (16 AIS, 4 JIS). In whole, six contaminated instances offered inside two weeks of the index process (acute an infection) and 4 contaminated instances offered a couple of yr from the index process (delayed an infection). The most typical presentation for acute infections was wound drainage, whereas again ache was extra widespread in delayed infections. All infections had been efficiently handled with surgical irrigation and debridement and postoperative antibiotics. was eliminated for sufferers with delayed infections. The strongest danger issue for an infection was elevated requirement for blood transfusion, nevertheless it didn’t attain statistical significance.
Conclusion: SSI with Propionibacterium acnes is a crucial complication after spinal fusion for idiopathic scoliosis. These infections may be efficiently handled, however bigger research are wanted to additional determine danger components and set up standardized tips for the therapy and prevention of this complication.
Stage of Proof Stage III:
PMID: 29707057 [PubMed]