Propionibacterium acnes infections in sufferers with idiopathic scoliosis: a case-control research and assessment of the literature.
J Little one Orthop. 2018 Apr 01;12(2):173-180
Authors: Swarup I, Gruskay J, Value M, Yang J, Blanco J, Perlman S, Widmann R
Goal: Surgical website an infection (SSI) brought on by Propionibacterium acnes is an rare however devastating complication after spinal fusion. The aim of this research was to determine danger elements for SSI with Propionibacterium acnes after spinal fusion for juvenile and adolescent idiopathic scoliosis (JIS and AIS).
Strategies: A case-control research was carried out. Every case was matched 2:1 for age, gender and analysis. Retrospective chart assessment was carried out to acquire related demographic, surgical and scientific information for all circumstances and controls. Statistical evaluation included paired t-test and McNemar check, in addition to actual logistic regression and sturdy regression fashions.
Outcomes: This research included ten an infection circumstances (eight AIS, two JIS) and 20 controls (16 AIS, 4 JIS). In whole, six contaminated circumstances introduced inside two weeks of the index process (acute an infection) and 4 contaminated circumstances introduced multiple 12 months from the index process (delayed an infection). The most typical presentation for acute infections was wound drainage, whereas again ache was extra widespread in delayed infections. All infections had been efficiently handled with surgical irrigation and debridement and postoperative antibiotics. was eliminated for sufferers with delayed infections. The strongest danger issue for an infection was elevated requirement for blood transfusion, however it didn’t attain statistical significance.
Conclusion: SSI with Propionibacterium acnes is a vital complication after spinal fusion for idiopathic scoliosis. These infections might be efficiently handled, however bigger research are wanted to additional determine danger elements and set up standardized pointers for the remedy and prevention of this complication.
Stage of Proof Stage III:
PMID: 29707057 [PubMed]