Main meningeal melanocytoma in sellar area, simulating a nonfunctioning pituitary adenoma; a case report and literature evaluate.
World Neurosurg. 2018 Jan 27;:
Authors: Wang F, Ling S
BACKGROUND: and Significance Main meningeal melanocytoma (PMM) is a benign lesion within the central nervous system derived from leptomeningeal melanocytes, mostly rising within the posterior fossa and cervical spinal wire. The first sellar melanocytoma is an exceptionally uncommon tumor. The authors reported the ninth revealed case of a sellar major meningeal melanocytoma (SPMM).
CLINICAL PRESENTATION: The affected person introduced solely with visible impairment and irregular menstruation with out different signs. Her basic examination was in any other case unremarkable. Endocrine investigations disclosed regular endocrine operate besides slight hyperprolactinemia. Magnetic resonance imaging revealed a sellar lesion. The affected person underwent a profitable complete transphenoidal elimination of the tumor with out neurological sequelae. Based mostly on the findings proven on this case report, the meningeal melanocytoma ought to be included within the differential prognosis of malignant and/or metastatic melanoma. The authors focus on the issues of differential prognosis and administration of major sellar melanocytic tumors.
CONCLUSIONS: The first sellar melanocytoma is an exceptionally uncommon tumor. Differentiating sellar melanocytic tumors from different sellar illnesses by medical and radiological investigations may be very tough. Therapy of major sellar melanocytic tumor ought to be full tumor elimination by surgical procedure. As for tumor partially resected, radiotherapy is an efficient complementary modality of remedy.
PMID: 29382618 [PubMed – as supplied by publisher]