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Main lung metastasis of glioblastoma multiforme with epidural spinal metastasis: Case report.

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Main lung metastasis of glioblastoma multiforme with epidural spinal metastasis: Case report.

J Clin Neurosci. 2017 Jul;41:97-99

Authors: Hoffman HA, Li CH, Everson RG, Strunck JL, Yong WH, Lu DC

Summary
Extracranial metastasis of glioblastoma multiforme (GBM) is uncommon, however has not too long ago been reported with rising frequency. GBM metastases sometimes current after a biopsy or resection of the first tumor. An in any other case wholesome 54year-old girl introduced with recurring pleural effusions initially believed to be from a main lung malignancy. The affected person subsequently skilled a generalized tonic clonic seizure and a proper temporal mind mass was found. The affected person later developed weak point and radiculopathy, and an extramedullary extradural mass spreading from C7 to T6 was found. She underwent resection of each central nervous system lesions in addition to a lung biopsy, and all pathologic specimens have been according to GBM. The case introduced is exclusive in that the affected person’s preliminary signs have been associated to her metastasis. Moreover, a purely epidural unfold of GBM that respects the leptomeninges and intramedullary parenchyma is extremely uncommon.

PMID: 28343918 [PubMed – indexed for MEDLINE]

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