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Pretic-I Was A Safe And Effective Artificial Cervical Disc Prosthesis–A Retrospective And Comparative Study With 5-Year Follow-Up London Spine

Cervical Disc ArthroplastyThe London Spine Unit : most experienced treatment facility in UKPublished article CDA with Pretic-I demonstrated a well-accepted and sustained clinical outcome, with a significantly lower incidence of high-grade HO. This newly designed prosthesis is expected to become an alternative choice for cervical disc prosthesis in the future.Cervical Disc Arthroplasty Expert. Best Spinal Surgeon UKThe London Spine Unit is a specialist clinic for Cervical Disc Arthoplasty as Day Surgery.

Abstract

Background: The newly designed cervical disc prosthesis, Pretic-I, had been finished its limited clinical use for over 5 years. At a short-term follow-up of 2 years, we obtained satisfactory clinical results. The long-term clinical efficacy and safety of Pretic-I will now be analyzed.

Methods: Peri-operative parameters included intra-operative blood loss, operation time, off-bed time. Clinical parameters included visual analogue scale (VAS) for arm and neck, neck disability index (NDI), and Japanese Orthopaedic Association (JOA) score. Radiological parameters included C2-7 Cobb angle, Shell angle, and the range of motion (ROM) of C2-7, functional segment unit (FSU), and adjacent FSU. The CDA-related complications included adjacent segment degeneration (ASDeg), adjacent segment disease (ASDis), heterotopic ossification (HO), prosthesis subsidence, prosthesis displacement, and dysphagia.

Results: A total 64 patients from two independent centers received a single-level CDA with Discover (n = 32) and Pretic-I (n = 32), and all of patients finished a 5-year follow-up. There’re no significant differences between two groups in peri-operative parameters. The clinical parameters improved greatly in Pretic-I group (p<0.0001), and there's no statistical difference from Discover group. Furthermore, Pretic-I could slightly improve the cervical curvature (15.08 ± 11.75 to 18.00 ± 10.61, p = 0.3079) and perfectly maintain the Shell angle (3.03 ± 3.68 to 2.23 ± 4.10, p = 0.1988), cervical ROM (52.48 ± 14.31 to 53.30 ± 11.71, p = 0.8062) and FSU ROM (12.20 ± 4.52 to 10.73 ± 4.45, p = 0.2002). The incidence of high-grade HO (Grade III-IV) at the final follow-up was significantly lower in Pretic-I group than in Discover group (12.50% vs. 34.38%, p = 0.0389, Statistical Power = 95.36%). The incidences of other CDA-related complications in Pretic-I group were also well-accepted, comparable to the Discover group, without significant differences.

CDA with Pretic-I demonstrated a well-accepted and sustained clinical outcome, with a significantly lower incidence of high-grade HO. This newly designed prosthesis is expected to become an alternative choice for cervical disc prosthesis in the future.

Keywords: Adjacent segment disease; Cervical disc arthroplasty; Discover; Heterotopic ossification; Pretic-I.

The London Spine Unit : most experienced treatment facility in UKRead the original publication from Pubmed : Pretic-I was a safe and effective artificial cervical disc prosthesis–a retrospective and comparative study with 5-year follow-up

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Ms Lisa Martin
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2021-12-27
Spinal Decompression and Stabilisation My experience at the London Spine Unit was excellent. Referred by a friend who had previously had a back operation and was very satisfied. All my lower back and leg pain gone and was up and walking two hours after procedure. Would highly recommend thank you Mr Akmal and Dr Lock 😊
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2021-12-23
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2021-11-10
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2021-09-09
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Abstract Background: The newly designed cervical disc prosthesis, Pretic-I, had been finished its limited clinical use for over 5 years. At a short-term follow-up of 2 years, we obtained satisfactory clinical results. The long-term clinical efficacy and safety of Pretic-I will now be analyzed. Methods: Peri-operative parameters included intra-operative blood loss, operation time, off-bed time.…

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