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Posterior surgical therapy of ankylosing spondylitis with spinal tuberculosis: A case sequence and long-term follow-up.

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Posterior surgical therapy of ankylosing spondylitis with spinal tuberculosis: A case sequence and long-term follow-up.

Drugs (Baltimore). 2018 Aug;97(34):e11925

Authors: Yin XH, Liu SC, Yang M, He BR, Liu ZK, Hao DJ

Summary
This retrospective cohort research aimed to judge the medical outcomes of posterior surgical therapy of ankylosing spondylitis (AS) with spinal tuberculosis (STB). This was a retrospective research together with 12 sufferers handled between January 2004 and April 2014 for AS with STB at our division. All sufferers underwent 1-stage posterior inside fixation, debridement, and bone fusion. The sufferers had been evaluated primarily based on the American Spinal Harm Affiliation (ASIA), kyphotic Cobb angle, and the visible analog rating (VAS). All sufferers had been adopted up for a median of 42.7?±?13.2 months after surgical procedure and bone fusion was achieved 6.eight?±?1.three months. In line with ASIA, 2 circumstances had been rated as Grade D, 10 circumstances had been Grade E finally follow-up. The typical preoperative Cobb angle was 26.7?±?7.6° (vary 15-36) and the typical postoperative Cobb angle was 7.eight?±?1.2° (vary 6-9). The imply newest follow-up Cobb angle was 9.1?±?1.zero° (vary 6-10). In contrast with the typical preoperative Cobb angle, there have been important variations relating to the kyphotic Cobb angle measured postoperatively and at closing follow-up (P?<?.05). The VAS considerably was significantly improved between the preoperative and the final medical visits. These optimistic outcomes reveal that 1-stage surgical therapy for AS with STB by posterior debridement, fusion, and instrumentation might be an efficient and possible therapy methodology for this particular situation. It needs to be famous that it’s obligatory to hold out antiosteoporosis therapy and carry out long-segmental instrumentation in an effort to acquire spinal stabilization.

PMID: 30142806 [PubMed – indexed for MEDLINE]

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