Percutaneous Injection of Strontium Containing Hydroxyapatite versus Polymethacrylate Plus Brief-Phase Pedicle Screw Fixation for Traumatic A2- and A3/AO-Sort Fractures in Adults.
Adv Orthop. 2018;2018:6365472
Authors: Korovessis P, Mpountogianni E, Syrimpeis V, Baikousis A, Tsekouras V
Introduction: Polymethacrylate (PMMA) is often utilized in vertebroplasty and balloon kyphoplasty, however its use has been related to issues. This examine exams three hypotheses: (1) whether or not strontium hydroxyapatite (Sr-HA) is equal to PMMA for restoring thoracolumbar vertebral physique fractures, (2) whether or not the incidence of PMMA leakage is much like that of Sr-HA leakage, and (three) whether or not Sr-HAis is resorbed and substituted by new vertebral bone.
Supplies and Strategies: Two age- and sex-matched teams obtained quick percutaneous pedicle screw fixation plus PEEK implant (Kiva, VCF Therapy System, Benvenue Medical, Santa Clara, CA, USA) stuffed with both Sr-HA (Group A) or PMMA (Group B) after A2- and A3/AO-type thoracolumbar vertebral physique fractures. The Visible Analog Scale (VAS) rating and imaging parameters, which included segmental kyphosis angle (SKA), vertebral physique top ratios (VBHr), spinal canal encroachment (SCE), bone cement leakage, and Sr-HA resorption, had been in contrast between the 2 teams.
Outcomes: The common follow-up was 28 months. No variations in VAS scores between Teams A and B had been noticed at baseline. Baseline again ache in each teams improved considerably three months postoperatively. Anterior, center, and posterior VBHr didn’t differ between the 2 teams at any time level. SKA was improved insignificantly in each teams. SCE decreased insignificantly in each teams on 12-month follow-up utilizing computed tomography (CT). PMMA leakage was noticed in a single affected person, whereas no Sr-HA paste leakages occurred. Sr-HA resorption and substitute with vertebral bone had been noticed, and no new fractures had been noticed.
Conclusions: As all hypotheses had been confirmed, the authors advocate using Sr-HA as an alternative of PMMA in traumatic backbone fractures, though extra sufferers and longer follow-up will likely be wanted to strengthen these outcomes. This trial is registered with NCT03431519.
PMID: 29692935 [PubMed]