19 Harley St, London, W1G 9QJ, UK

Orthopaedic manifestations in a case of Lenz microphthalmia syndrome

BACKGROUND: Lenz microphthalmia syndrome is an X-linked recessive disorder characterized by microphthalmia and dental, urogenital, and skeletal anomalies. This case report represents the first detailed account of congenital kyphoscoliosis in the Lenz microphthalmia literature. METHODS: We present a case of Lenz microphthalmia syndrome with progressive kyphosis, spinal stenosis, and late-onset tibia vara along with many of the typical features of the disorder. In addition, we provide insight into the syndrome by reviewing the existing Lenz microphthalmia literature. RESULTS: Congenital kyphoscoliosis that is prone to reoccurrence after posterior spinal fusion is an unusual entity that may be associated with Lenz microphthalmia. CONCLUSIONS: We recommend close monitoring and early surgical intervention with posterior spinal fusion for congenital kyphosis in patients diagnosed with Lenz microphthalmia syndrome. However, more data on similar patients are necessary to define the optimal treatment strategy. LEVEL OF EVIDENCE (FOR CLINICAL ARTICLES): Level V

Keywords : Adolescent,Anophthalmos,Bone Diseases,Developmental,congenital,Follow-Up Studies,Humans,Kyphosis,Male,methods,Microphthalmos,Osteochondrosis,Patients,Philadelphia,physiopathology,Scoliosis,Spinal Fusion,Spinal Stenosis,surgery,Syndrome,Tibia,Universities,, Manifestations, private cortisone injection

Date of Publication : 2011 Sep

Authors : Derman PB;Kulkarni SS;Dormans JP;

Organisation : University of Pennsylvania School of Medicine, Children’s Hospital of Philadelphia, Philadelphia, PA, USA

Journal of Publication : J Pediatr Orthop

Pubmed Link : https://www.ncbi.nlm.nih.gov/pubmed/21841432

The London Spine Unit : Harley Street UK. Specialists in Cutting Edge Technologies for Spinal Surgery

Make an Appointment 

Trustpilot Reviews
Doctify Reviews
Top Doctor Reviews

Orthopaedic manifestations in a case of lenz microphthalmia syndrome | Trigger points neck

What our patients say ...

Consultant Spine Surgeon
Consultant Spine Surgeon
Consultant Spine Surgeon

This surgical technique consists of a percutaneous approach for the treatment of small to medium size hernias of the intervertebral disc by laser energy. The main objective is to reduce the intradiscal pressure in the nucleus pulposus

Laser Disc Surgery can be performed under local anaesthetic as a day case at our centre on the prestigious Harley Street.
What is London spine unit and How it Works

The London Spine Unit was established in 2005 and has successfully treated over 5000 patients. All conditions are treated.

treatment of all spinal disorders

The London Spine Unit specialises in Minimally Invasive Treatments allowing rapid recovery and return to normal function

Trusted by patients worldwide

The London Spine Unit provides the highest quality care to all patients and has VIP services for those seeking exceptional services

If you have any emergency Doctor’s need, simply call our 24 hour emergency

Your personal case manager will ensure that you receive the best possible care.

Call Now 

+44 844 589 2020
+44 203 973 8810