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Myelopathy from Intradural Extramedullary Metastasis as an Preliminary Presentation of Metastatic Melanoma.

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Myelopathy from Intradural Extramedullary Metastasis as an Preliminary Presentation of Metastatic Melanoma.

Cureus. 2018 Could 22;10(5):e2668

Authors: Stein AA, Weinstein GR, Niezgoda C, Chowdhary S, Vrionis F, Houten JK

Summary
The incidence of metastatic melanoma (MM) has been steadily rising, and it’s the third most typical metastatic lesion to the central nervous system (CNS). Spinal intradural extramedullary (IDEM) MM is uncommon, and it’s related to coexisting or antecedent mind metastasis. Metastatic illness to the CNS is a complication of superior illness, and it usually happens months to years after preliminary analysis and therapy. We describe the primary case of an preliminary presentation of MM, presenting as cervical myelopathy secondary to spinal twine compression from IDEM spinal metastasis. Additional work-up revealed further lesions within the temporal lobe and cauda equina area in addition to a scalp lesion that was presumed to be the first website. MM needs to be thought-about within the differential of myelopathy secondary to a spinal intradural mass, significantly in these with a historical past of or threat elements for melanoma.

PMID: 30042919 [PubMed]

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