A number of vertebral fractures related to glucocorticoid-induced osteoporosis handled with teriparatide adopted by kyphosis correction fusion: a case report.
Osteoporos Int. 2018 Feb 23;:
Authors: Uei H, Tokuhashi Y, Maseda M, Nakahashi M, Nakayama E
Surgical therapy of a number of vertebral fractures in sufferers with glucocorticoid-induced osteoporosis is tough due to a excessive price of secondary fracture postoperatively. A case is described during which preliminary therapy with teriparatide to enhance osteoporosis adopted by therapy of kyphosis with correction fusion achieved a positive end result.
INTRODUCTION: Secondary fracture often happens after therapy of vertebral fracture with vertebroplasty and balloon kyphoplasty in sufferers with glucocorticoid-induced osteoporosis, however efficient therapy of a number of vertebral fractures has hardly ever been reported. Thus, a therapy of kyphosis following a number of vertebral fractures related to glucocorticoid-induced osteoporosis is required.
METHODS: The affected person was a 24-year-old lady identified with glucocorticoid-induced osteoporosis who was beneath therapy with oral alendronate, vitamin D, and elcatonin injection. Secondary a number of vertebral fractures occurred regardless of these therapies and low again ache steadily aggravated.
RESULTS: Vertebroplasty or balloon kyphoplasty was not carried out within the early section. As an alternative, therapy with teriparatide was used for preliminary enchancment of osteoporosis. Kyphosis within the heart of the residual thoracolumbar junction was then handled with posterior correction fusion. At 2 years after surgical procedure, the corrected place has been maintained and no new fracture has occurred.
CONCLUSION: There isn’t any established technique for therapy of a number of vertebral fractures brought on by glucocorticoid-induced osteoporosis. Preliminary therapy with teriparatide to enhance osteoporosis adopted by therapy of kyphosis with correction fusion might lead to a extra favorable end result.
PMID: 29476202 [PubMed – as supplied by publisher]