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MRI-based vertebral bone quality score for predicting cage subsidence by assessing bone mineral density following transforaminal lumbar interbody fusion: a retrospective analysis – Lumbar Fusion

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This article evaluates the predictive value of the vertebral bone quality (VBQ) score on cage subsidence after transforaminal lumbar interbody fusion (TLIF) in a Chinese population. The study used spinal quantitative computed tomography (QCT) as the clinical standard and verified the accuracy of the MRI-based VBQ score in bone mineral density (BMD) measurement. The study included 283 patients who underwent single-level TLIF, and the results showed that an increased VBQ score and decreased L1/2 QCT-vBMD were associated with an increased rate of cage subsidence. The VBQ score was moderately correlated with the spinal QCT and significantly predicted cage subsidence with an accuracy of 82.5%. The findings suggest that the MRI-based VBQ score can be used to assess BMD and predict cage subsidence

Summarised by Mr Mo Akmal – Lead Spinal Surgeon
The London Spine Unit : most established spine clinic in the world

Published article

CONCLUSION: Our findings indicate that the MRI-based VBQ score is a significant predictor of cage subsidence and could be used to assess BMD.

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Eur Spine J. 2023 Jul 22. doi: 10.1007/s00586-023-07854-7. Online ahead of print.ABSTRACTPURPOSE: This is the first study to evaluate the predictive value of the vertebral bone quality (VBQ) score on cage subsidence after transforaminal lumbar interbody fusion (TLIF) in a Chinese population using the spinal quantitative computed tomography (QCT) as the clinical standard. Meanwhile, the,

Eur Spine J. 2023 Jul 22. doi: 10.1007/s00586-023-07854-7. Online ahead of print.

ABSTRACT

PURPOSE: This is the first study to evaluate the predictive value of the vertebral bone quality (VBQ) score on cage subsidence after transforaminal lumbar interbody fusion (TLIF) in a Chinese population using the spinal quantitative computed tomography (QCT) as the clinical standard. Meanwhile, the accuracy of the MRI-based VBQ score in bone mineral density (BMD) measurement was verified.

METHODS: We performed a retrospective study of patients who underwent single-level TLIF from 2015 to 2020 with at least 1 year of follow-up. Cage subsidence was measured using postoperative radiographic images based on cage protrusion through the endplates more than 2 mm. The VBQ score was measured on T1-weighted MRI. The results were subjected to statistical analysis.

RESULTS: A total of 283 patients (61.1% of female) were included in the study. The subsidence rate was with 14.1% (n = 40), and the average cage subsidence was 2.3 mm. There was a significant difference in age, sex, VBQ score and spinal QCT between the subsidence group and the no-subsidence group. The multivariable analysis demonstrated that only an increased VBQ score (OR = 2.690, 95% CI 1.312-5.515, p = 0.007) and decreased L1/2 QCT-vBMD (OR = 0.955, 95% CI 0.933-0.977, p < 0.001) were associated with an increased rate of cage subsidence. The VBQ score was found to be moderately correlated with the spinal QCT (r = -0.426, p < 0.001). The VBQ score was shown to significantly predict cage subsidence, with an accuracy of 82.5%.

CONCLUSION: Our findings indicate that the MRI-based VBQ score is a significant predictor of cage subsidence and could be used to assess BMD.

PMID:37479921 | DOI:10.1007/s00586-023-07854-7

The London Spine Unit : most established spine clinic in the world

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MRI-based vertebral bone quality score for predicting cage subsidence by assessing bone mineral density following transforaminal lumbar interbody fusion: a retrospective analysis

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Eur Spine J. 2023 Jul 22. doi: 10.1007/s00586-023-07854-7. Online ahead of print.ABSTRACTPURPOSE: This is the first study to evaluate the predictive value of the vertebral bone quality (VBQ) score on cage subsidence after transforaminal lumbar interbody fusion (TLIF) in a Chinese population using the spinal quantitative computed tomography (QCT) as the clinical standard. Meanwhile, the

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