Most effective questionnaires to measure high quality of life, bodily operate, and ache in sufferers with metastatic backbone illness: a cross-sectional potential survey examine.
Backbone J. 2017 Jul;17(7):953-961
Authors: Paulino Pereira NR, Janssen SJ, Raskin KA, Hornicek FJ, Ferrone ML, Shin JH, Bramer JAM, van Dijk CN, Schwab JH
BACKGROUND CONTEXT: Assessing high quality of life, useful final result, and ache has change into vital in assessing the effectiveness of remedy for metastatic backbone illness. Many questionnaires are in a position to measure these outcomes; few are validated in sufferers with metastatic backbone illness. Because of this, there is no such thing as a consensus on the perfect questionnaire to make use of in these sufferers.
PURPOSE: Our examine intention was to evaluate whether or not sure questionnaires measuring high quality of life, useful final result, and ache (1) correlated with one another, (2) measured the assemble they declare to measure, (three) had good coverage-floor and ceiling results, (four) have been dependable, and (5) whether or not there have been variations in completion time between them.
DESIGN: This can be a potential cross-sectional survey examine from three outpatient clinics (two orthopedic oncology clinics and one neurosurgery clinic) from two affiliated tertiary hospital care facilities.
PATIENT SAMPLE: We included 100 consecutive sufferers with metastatic backbone illness between July 2014 and February 2016. We excluded non-English-speaking sufferers.
OUTCOME MEASURES: The next questionnaires got in random order: Oswestry Incapacity Index (ODI) or Neck Incapacity Index (NDI), Affected person-Reported Outcomes Measurement Info System (PROMIS) Bodily Perform, PROMIS Ache Depth, EuroQol-5 Dimensions (EQ-5D), and the Backbone Oncology Research Group End result Questionnaire (SOSG-OQ).
METHODS: We used exploratory issue analysis-correlating questionnaires with an underlying mathematically derived trait-to assess if questionnaires measured the identical idea. Protection was assessed by flooring and ceiling results, and reliability was assessed by normal error of measurement as a operate of means. Variations in completion occasions have been examined utilizing the Friedman check.
RESULTS: Questionnaires measured the assemble they have been developed for, as demonstrated with excessive correlations (>zero.7) with the underlying trait. A flooring impact was current within the PROMIS Ache Depth (7.zero%), ODI or NDI (four.zero%), and the PROMIS Bodily Perform (1.zero%) questionnaires. A ceiling impact was current within the EQ-5D questionnaire (6.zero%). The SOSG-OQ had no flooring or ceiling impact. The PROMIS Bodily Perform and PROMIS Ache Depth proved to be essentially the most dependable, whereas the EQ-5D was the least dependable. Completion time differed amongst questionnaires (p<.001) and was shortest for the PROMIS Ache Depth (median 24 seconds) and PROMIS Bodily Perform (median 42 seconds).
CONCLUSIONS: In sufferers with metastatic backbone illness, we advocate the SOSG-OQ for measuring high quality of life, the PROMIS Bodily Perform for measuring bodily operate, and the PROMIS Ache Depth for measuring ache.
PMID: 28242336 [PubMed – indexed for MEDLINE]