19 Harley St, London, W1G 9QJ, UK
We are London's Top Spine Clinic

Methadone and oedema in the palliative care setting: a case report and review of the literature.

Related Articles

Methadone and oedema in the palliative care setting: a case report and review of the literature.

Scott Med J. 2014 Mar 27;

Authors: Dawson C, Paterson F, McFatter F, Buchanan D

INTRODUCTION: Methadone is a synthetic opioid which is being used with increased frequency in the palliative care setting for management of complex pain. There have been cases published reporting the development of oedema with methadone maintenance therapy but no cases on the association with methadone and peripheral oedema in the palliative care setting. As yet, the underlying mechanisms are unclear.
CASE PRESENTATION: This case report describes a gentleman with ependymoma and difficult-to-control lower back pain and scrotal pain. This pain had failed to respond to other strong opioids. He was prescribed methadone and then subsequently developed bilateral peripheral oedema.
CASE MANAGEMENT: Peripheral oedema resolved following cessation of methadone.
CONCLUSIONS: This highlights an important potential adverse effect of methadone in a society of increased methadone prescription for pain control. The published literature to date is reviewed and possible underlying mechanisms explored.

PMID: 24676025 [PubMed – as supplied by publisher]

Share to care...

Share on facebook
Share on twitter
Share on pinterest
Share on google
Share on linkedin
Share on skype

What we do...

The Harley Street Hospital


What is London spine unit and How it Works

The London Spine Unit was established in 2005 and has successfully treated over 5000 patients. All conditions are treated.

We treat all spinal disorders

The London Spine Unit specialises in Minimally Invasive Treatments allowing rapid recovery and return to normal function

Trusted by patients worldwide

The London Spine Unit provides the highest quality care to all patients and has VIP services for those seeking exceptional services

What our patients say about us ......