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Meta-analysis of the efficacy and safety of OLIF and TLIF in the treatment of degenerative lumbar spondylolisthesis – Lumbar Fusion

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The article systematically evaluated the clinical efficacy difference between two surgical approaches, oblique lateral approach, and intervertebral foraminal approach, in the treatment of degenerative lumbar spondylolisthesis. The study included a total of 14 studies with 877 patients, comparing the outcomes of OLIF and TLIF. The results showed that OLIF had several advantages over TLIF, including shorter surgical duration, reduced intraoperative bleeding, shorter hospital stay, better improvement in postoperative VAS and ODI scores, better restoration of disc height, and more effective correction of lumbar lordosis. However, there were no significant differences in terms of surgical complications and fusion rates between the two approaches. The study concluded that OLIF is more beneficial in treating degenerative lumbar spondylolisthesis compared to TLIF

Summarised by Mr Mo Akmal – Lead Spinal Surgeon
The London Spine Unit : the highest rated spine clinic on Harley Street UK

Published article

: When treating degenerative lumbar spondylolisthesis, OLIF demonstrates significant advantages over TLIF in terms of shorter surgical duration, reduced intraoperative bleeding, shorter hospital stay, superior improvement in postoperative VAS and ODI scores, better restoration of disc height, and more effective correction of lumbar lordosis.

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J Orthop Surg Res. 2024 Apr 15;19(1):242. doi: 10.1186/s13018-024-04703-1. ABSTRACT OBJECTIVE: To systematically evaluate the difference in clinical efficacy between two surgical approaches, oblique lateral approach and intervertebral foraminal approach, in the treatment of degenerative lumbar spondylolisthesis. METHODS: English databases, including PubMed, Cochrane, Embase, and Web of Science, were systematically searched using keywords such as,

J Orthop Surg Res. 2024 Apr 15;19(1):242. doi: 10.1186/s13018-024-04703-1.

ABSTRACT

OBJECTIVE: To systematically evaluate the difference in clinical efficacy between two surgical approaches, oblique lateral approach and intervertebral foraminal approach, in the treatment of degenerative lumbar spondylolisthesis.

METHODS: English databases, including PubMed, Cochrane, Embase, and Web of Science, were systematically searched using keywords such as “oblique lumbar interbody fusion” and “transforaminal lumbar interbody fusion.” Concurrently, Chinese databases, including CNKI, WanFang data, VIP, and CBM, were also queried using corresponding Chinese terms. The search spanned from January 2014 to February 2024, focusing on published studies in both Chinese and English that compared the clinical efficacy of OLIF and TLIF. The literature screening was conducted by reviewing titles, abstracts, and full texts. Literature meeting the inclusion criteria underwent quality assessment, and relevant data were extracted. Statistical analysis and a meta-analysis of the observational data for both surgical groups were performed using Excel and RevMan 5.4 software. Findings revealed a total of 14 studies meeting the inclusion criteria, encompassing 877 patients. Of these, 414 patients were in the OLIF group, while 463 were in the TLIF group. Meta-analysis of the statistical data revealed that compared to TLIF, OLIF had a shorter average surgical duration (P < 0.05), reduced intraoperative bleeding (P < 0.05), shorter average hospital stay (P < 0.05), better improvement in postoperative VAS scores (P < 0.05), superior enhancement in postoperative ODI scores (P < 0.05), more effective restoration of disc height (P < 0.05), and better correction of lumbar lordosis (P < 0.05). However, there were no significant differences between OLIF and TLIF in terms of the incidence of surgical complications (P > 0.05) and fusion rates (P > 0.05).

: When treating degenerative lumbar spondylolisthesis, OLIF demonstrates significant advantages over TLIF in terms of shorter surgical duration, reduced intraoperative bleeding, shorter hospital stay, superior improvement in postoperative VAS and ODI scores, better restoration of disc height, and more effective correction of lumbar lordosis.

PMID:38622724 | PMC:PMC11020183 | DOI:10.1186/s13018-024-04703-1

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Meta-analysis of the efficacy and safety of OLIF and TLIF in the treatment of degenerative lumbar spondylolisthesis

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J Orthop Surg Res. 2024 Apr 15;19(1):242. doi: 10.1186/s13018-024-04703-1. ABSTRACT OBJECTIVE: To systematically evaluate the difference in clinical efficacy between two surgical approaches, oblique lateral approach and intervertebral foraminal approach, in the treatment of degenerative lumbar spondylolisthesis. METHODS: English databases, including PubMed, Cochrane, Embase, and Web of Science, were systematically searched using keywords such as

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