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Meningeal carcinomatosis: three case-reports.

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Meningeal carcinomatosis: three case-reports.

World J Surg Oncol. 2018 Apr 13;16(1):78

Authors: Chen G, Ma L, Xu M, Wang X, Wang C, Zhao C, Zhang J

Summary
BACKGROUND: Meningeal carcinomatosis (MC) is characterised by diffuse infiltration of tumor cells in meninges. There isn’t any tumor mass within the mind and parenchyma of the spinal twine. MC is split into major and metastatic varieties. MC instances had been beforehand identified postoperatively or at post-mortem. Latest advances in spinal abbreviation cytology and imaging have led to extend in variety of reported instances. On this research, we talk about the manifestations of MC sufferers primarily based on magnetic resonance imaging (MRI) findings, in addition to the correlation between the manifestations and pathology.
CASE PRESENTATION: MC was confirmed in all three instances by lumbar puncture and gadopentetate dimeglumine-enhanced magnetic resonance imaging. As a result of totally different major ailments, the sufferers had particular imaging manifestations.
CONCLUSION: Enhanced MRI examination is extraordinarily delicate for detecting abnormalities in meninges, which performs an important function within the analysis of MC. Since meninges of some MC sufferers can’t be enhanced, the improved MRI examination can’t be changed by typical cerebrospinal abbreviation examination. Attribute to the range of MR distinction brokers, which might present increased lesion conspicuity and enhances lesion detection, there could also be some extra decisions to enhance the detection price of MC sufferers and lengthen their survival lifetime.

PMID: 29653576 [PubMed – in process]

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