19 Harley St, London, W1G 9QJ, UK
We are London's Top Spine Clinic

[Melanocytoma and meningeal melanocytosis, similar but different lesions].

Related Articles

[Melanocytoma and meningeal melanocytosis, similar but different lesions].

Cir Cir. 2017 Might – Jun;85(three):273-278

Authors: Padilla-Vázquez F, Escobar-de la Garma VH, Ayala-Arcipreste A, Mendizábal-Guerra R, Cuesta-Mejía T

BACKGROUND: Meningeal melanomatosis is an extra-axial well-encapsulated malignant tumour with diffuse meningeal development and darkish coloration (because of excessive melanin contents), whereas meningeal melanocytoma is the focalized benign variant. Melanocytic lesions could also be secondary to melanoma or be histologically benign, nevertheless, their diffuse nature makes them unattainable to remedy. Melanocytosis is a diffuse tumour that may type solitary extra-axial tumours, which invades the parenchyma and presents indicators of malignancy with elevated mitosis and Ki67, noticed in 1 to six% of immunopathological exams. Melanoma of the leptomeninges, presents indicators of malignancy with anaplastic cells, which cluster in fascicles of melanin within the cytoplasm, with greater than three atypical mitoses per area and Ki67 presenting in additional than 6% of the immunopathological fields analysed.
CLINICAL CASE: We current the case of a affected person with long-term meningeal melanomatosis, with progressive neurologic deficit and attribute radiologic options, and one other case of meningeal melanocytoma.
CONCLUSIONS: Benign melanocytic neoplasms of the central nervous system should be handled aggressively within the early phases with strict follow-up to keep away from development to superior phases that don’t reply to any remedy methodology. Sadly, the prognosis for malignant melanocytic lesions may be very poor regardless of the tactic of remedy given.

PMID: 28126183 [PubMed – indexed for MEDLINE]

Share to care...

Share on facebook
Share on twitter
Share on pinterest
Share on google
Share on linkedin
Share on skype

What we do...

The Harley Street Hospital


What is London spine unit and How it Works

The London Spine Unit was established in 2005 and has successfully treated over 5000 patients. All conditions are treated.

We treat all spinal disorders

The London Spine Unit specialises in Minimally Invasive Treatments allowing rapid recovery and return to normal function

Trusted by patients worldwide

The London Spine Unit provides the highest quality care to all patients and has VIP services for those seeking exceptional services

What our patients say about us ......

Patient with degenerative disc

Arrangements at the hospital were all excellent. Bernard G. You May Also Like:Spinal Injection for Lower Back PainDisc prolapsePatient with Lumbar StenosisPatient suffering from severe

Read More »