A novel biomimetic artificial intervertebral disc (bioAID) replacement implant has been developed, which consists of a swelling hydrogel representing the nucleus pulposus, a fiber jacket as annulus fibrosus, and titanium endplates with pins to secure the device between the vertebral bodies. The design safety of this implant was evaluated through various biomechanical parameters, including compressive strength, shear-compressive strength, risk of subsidence and device expulsion, and diurnal creep-recovery characteristics. The results showed that the bioAID remained intact up to 1 kN under static axial compression and had minimal translation under compressive shear loads. No subsidence was observed after repeated compressive loading, and the displacement of the implant was within the range of other cervical disc replacement devices. The bioAID also demonstrated diurnal creep recovery behavior similar to natural discs. Overall, this implant can withstand loads and mimic the behavior of natural discs, making it a promising option for cervical disc replacement
Summarised by Mr Mo Akmal – Lead Spinal Surgeon
The London Spine Unit : the highest rated spine clinic on Harley Street UK
Published article
A novel biomimetic artificial intervertebral disc (bioAID) replacement implant has been developed containing a swelling hydrogel representing the nucleus pulposus, a tensile strong fiber jacket as annulus fibrosus and titanium endplates with pins to primarily secure the device between the vertebral bodies. In this study, the design safety of this novel implant was evaluated based on several biomechanical parameters, namely compressive strength, shear-compressive strength, risk of subsidence and…
Lumbar Disc Replacement Surgery Expert. Best Spinal Surgeon UK
Abstract A novel biomimetic artificial intervertebral disc (bioAID) replacement implant has been developed containing a swelling hydrogel representing the nucleus pulposus, a tensile strong fiber jacket as annulus fibrosus and titanium endplates with pins to primarily secure the device between the vertebral bodies. In this study, the design safety of this novel implant was evaluated,
Abstract
A novel biomimetic artificial intervertebral disc (bioAID) replacement implant has been developed containing a swelling hydrogel representing the nucleus pulposus, a tensile strong fiber jacket as annulus fibrosus and titanium endplates with pins to primarily secure the device between the vertebral bodies. In this study, the design safety of this novel implant was evaluated based on several biomechanical parameters, namely compressive strength, shear-compressive strength, risk of subsidence and device expulsion as well as identifying the diurnal creep-recovery characteristics of the device. The bioAID remained intact up to 1 kN under static axial compression and only 0.4 mm of translation was observed under a compressive shear load of 20 N. No subsidence was observed after 0.5 million cycles of sinusoidal compressive loading between 50 and 225 N. After applying 400 N in antero-posterior direction under 100 N axial compressive preload, approximately 2 mm displacement was found, being within the range of displacements reported for other commercially available cervical disc replacement devices. The diurnal creep recovery behavior of the bioAID closely resembled what has been reported for natural intervertebral discs in literature. Overall, these results indicate that the current design can withstand (shear-compression loads and is able to remain fixed in a mechanical design resembling the vertebral bodies. Moreover, it is one of the first implants that can closely mimic the poroelastic and viscoelastic behavior of natural disc under a diurnal loading pattern.
Keywords: Biomechanical; Biomimetic; Cervical disc replacement.
The London Spine Unit : the highest rated spine clinic on Harley Street UK
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Mechanical characterization of a novel biomimetic artificial disc for the cervical spine
