A biomimetic artificial intervertebral disc (bioAID) replacement implant has been developed, consisting of a hydrogel nucleus pulposus, fiber jacket annulus fibrosus, and titanium endplates. The safety and biomechanical characteristics of the implant were evaluated, including compressive strength, shear-compressive strength, risk of subsidence and device expulsion, and diurnal creep-recovery behavior. The bioAID showed good performance, withstanding compressive and shear loads, remaining fixed between vertebral bodies, and displaying similar behavior to natural intervertebral discs. This implant is one of the first to closely mimic the biomechanics of natural discs and could be a promising option for cervical disc replacement
Summarised by Mr Mo Akmal – Lead Spinal Surgeon
The London Spine Unit : innovative treatment facility in the world
Published article
A novel biomimetic artificial intervertebral disc (bioAID) replacement implant has been developed containing a swelling hydrogel representing the nucleus pulposus, a tensile strong fiber jacket as annulus fibrosus and titanium endplates with pins to primarily secure the device between the vertebral bodies. In this study, the design safety of this novel implant was evaluated based on several biomechanical parameters, namely compressive strength, shear-compressive strength, risk of subsidence and…
Cervical Disc Replacement Surgery Expert. Best Spinal Surgeon UK
Abstract A novel biomimetic artificial intervertebral disc (bioAID) replacement implant has been developed containing a swelling hydrogel representing the nucleus pulposus, a tensile strong fiber jacket as annulus fibrosus and titanium endplates with pins to primarily secure the device between the vertebral bodies. In this study, the design safety of this novel implant was evaluated,
Abstract
A novel biomimetic artificial intervertebral disc (bioAID) replacement implant has been developed containing a swelling hydrogel representing the nucleus pulposus, a tensile strong fiber jacket as annulus fibrosus and titanium endplates with pins to primarily secure the device between the vertebral bodies. In this study, the design safety of this novel implant was evaluated based on several biomechanical parameters, namely compressive strength, shear-compressive strength, risk of subsidence and device expulsion as well as identifying the diurnal creep-recovery characteristics of the device. The bioAID remained intact up to 1 kN under static axial compression and only 0.4 mm of translation was observed under a compressive shear load of 20 N. No subsidence was observed after 0.5 million cycles of sinusoidal compressive loading between 50 and 225 N. After applying 400 N in antero-posterior direction under 100 N axial compressive preload, approximately 2 mm displacement was found, being within the range of displacements reported for other commercially available cervical disc replacement devices. The diurnal creep recovery behavior of the bioAID closely resembled what has been reported for natural intervertebral discs in literature. Overall, these results indicate that the current design can withstand (shear-compression loads and is able to remain fixed in a mechanical design resembling the vertebral bodies. Moreover, it is one of the first implants that can closely mimic the poroelastic and viscoelastic behavior of natural disc under a diurnal loading pattern.
Keywords: Biomechanical; Biomimetic; Cervical disc replacement.
The London Spine Unit : innovative treatment facility in the world
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Mechanical characterization of a novel biomimetic artificial disc for the cervical spine
