Malignant peripheral nerve sheath tumor within the paraspinal area mimicking a benign peripheral nerve sheath tumor: a case report.
Eur Backbone J. 2017 Could;26(Suppl 1):90-94
Authors: Pan W, Feng B, Wang Z, Lin N, Ye Z
PURPOSE: Malignant peripheral nerve sheath tumors are extraordinarily uncommon within the common inhabitants and show a predilection for metastasis to the lungs. Right here, we current a uncommon case of a malignant peripheral nerve sheath tumor situated within the paraspinal area and spotlight the significance of preoperative biopsy in analysis of spinal epidural peripheral nerve sheath tumors.
METHODS: We describe the scientific course of the affected person in addition to the radiological and pathological findings of the tumor.
RESULTS: A 14-year-old woman introduced with a six-month historical past of sacral ache. Sometimes she skilled left leg ache and irregular gait. Common bodily examination revealed sensorial loss within the L5-S1 areas. T1-weighted sagittal MRI confirmed a hypointense oval mass and the contrast-enhanced T1-weighted axial MRI picture confirmed heterogeneous enhancement of the tumor. On CT imaging, this tumor characteristically seems as a dumbbell-like mass with punctate calcification and widening L5-S1 intervertebral foramen. Full resection was carried out utilizing an anterior method. Intraoperative pathological examination revealed proof of malignancy and subsequent immunohistochemical evaluation of the tumor confirmed the analysis of MPNST. The postoperative course was uneventful and the affected person has had vital enchancment in her signs 1 month postoperatively.
CONCLUSIONS: Preoperative biopsy needs to be routinely carried out for pathological differential analysis of spinal epidural PNSTs in addition to surgical decision-making. Moreover a mixture of scientific manifestation, radiological findings and biopsy must also be pursued for diagnosing these tumors.
PMID: 27679432 [PubMed – indexed for MEDLINE]