Lumbar subtotal corpectomy non-fusion mannequin produced utilizing a novel prosthesis.
Arch Orthop Trauma Surg. 2017 Nov;137(11):1467-1476
Authors: Liu J, Zhang F, Gao Z, Li Y, Niu B, He X
OBJECTIVE: On this examine, we aimed to design a movable synthetic lumbar complicated (MALC) prosthesis for non-fusion reconstruction after lumbar subtotal corpectomy and to determine an in vitro anterolateral lumbar corpectomy non-fusion mannequin for evaluating the biomechanical stability, preservation of phase actions and affect on adjoining inter-vertebral actions of this prosthesis.
METHODS: Imaging was carried out on a complete of 26 recent goat lumbar backbone specimens to find out which of the specimens didn’t meet the necessities (freed from deformity and fractures); the residual specimens had been randomly divided into an intact group, a fusion group and a non-fusion group. Bone mineral density (BMD) was examined and in contrast among the many three teams. Biomechanical testing was carried out to acquire the vary of movement (ROM) in flexion-extension, lateral bending at L2-Three, L3-Four and L4-5 and axial rotation at L2-5 within the three teams.
RESULTS: Two specimens had been excluded because of vertebral fractures. BMD confirmed no statistical significance amongst three teams (P > zero.05). The steadiness of the prosthesis didn’t differ considerably throughout flexion, extension, and lateral bending at L2-Three, L3-Four, and L4-5 and axial torsion at L2-5 between the intact group and the non-fusion group (P > zero.05). Section actions of the specimens within the non-fusion group revealed considerably decreased L2-Three ROM and considerably elevated L3-Four and L4-5 ROM in flexion and lateral bending in contrast with the fusion group (P < zero.05).
CONCLUSIONS: Reconstruction with a MALC prosthesis after lumbar subtotal corpectomy not solely produced immediate stability but in addition successfully preserved phase actions, with none irregular acquire of mobility in adjoining inter-vertebral areas. Nonetheless, extra research, together with in vivo animal experiments in addition to biocompatibility and biomechanical checks of human physique specimens are wanted.
PMID: 28889244 [PubMed – indexed for MEDLINE]