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Lumbar spondylolysis: A report of 4 instances from two generations of a household.
J Orthop Surg (Hong Kong). 2017 Could-Aug;25(2):2309499017713917
Authors: Yurube T, Kakutani Ok, Okamoto Ok, Manabe M, Maeno Ok, Yoshikawa M, Sha N, Kuroda R, Nishida Ok
Summary
Spondylolysis is a serious reason for again ache in kids and adolescents. The prevalence of spondylolysis is dependent upon the intercourse, race, and congenital abnormality. These biases counsel hereditary predisposition as an etiology of spondylolysis. Nevertheless, no conclusive proof nonetheless exists concerning the inheritance for spondylolysis. Herein, we report uncommon instances with familial incidence of lumbar spondylolysis. In two generations of a Japanese household, three brothers together with an identical twins complained of again ache associated to sports activities actions. Scientific, radiographic, and computed tomographic examinations recognized spondylolysis at L4 and L5 in all these boys. The daddy skilled long-term again ache and had spondylolisthesis at L4-L5 and healed spondylolysis at L5. The daughter and mom didn’t present any lumbar spondylolysis. The frequent growth of spondylolysis at L4, a not often affected phase, in 4 of six relations (66.7%) assist that lumbar spondylolysis has an underlying genetic etiology, primarily autosomal dominant inheritance.
PMID: 28617180 [PubMed – indexed for MEDLINE]