Live Video Consultation
19 Harley St, London, W1G 9QJ, UK

Lengthy-Time period Comply with-Up of Sufferers with Metastatic Epidural Spinal Twine Compression from Stable Tumors Submitted for Surgical procedure Adopted by Radiation Remedy.

Related Articles

Lengthy-Time period Comply with-Up of Sufferers with Metastatic Epidural Spinal Twine Compression from Stable Tumors Submitted for Surgical procedure Adopted by Radiation Remedy.

World Neurosurg. 2018 Jul;115:e681-e687

Authors: Pessina F, Navarria P, Carta GA, D’Agostino GR, Clerici E, Nibali MC, Costa F, Fornari M, Scorsetti M

Summary
OBJECTIVE: To guage the end result of sufferers with epidural spinal twine compression from totally different stable tumors handled with a mixed strategy, surgical procedure plus radiotherapy (RT), with a follow-up longer than 10 years.
METHODS: Ninety-seven sufferers handled between 2002 and 2009 have been included. Surgical remedy was carried out in sufferers with good efficiency standing, restricted metastatic illness, life expectancy longer than three months, and progressive neurologic deficit and/or intractable ache. RT was carried out delivering a median whole dose of 30 Gy in 10 fractions. Medical end result was evaluated utilizing the modified visible analog scale for ache, the Frankel scale for neurologic deficit, and magnetic resonance imaging earlier than remedy, after remedy, and each three months thereafter.
RESULTS: Palliative decompression was carried out in 27% of sufferers, tumor curettage (debulking) was carried out in 51%, and whole vertebrectomy was carried out in 22%, adopted by RT in 78% of circumstances. Ache remission was obtained in 98% of sufferers, and restoration of neurologic operate was obtained in 51%. The median follow-up time was 135 months (vary, 96-209 months). The 5- and 10-year native management charges have been 82.eight% and 82.eight%, respectively. The median and 5- and 10-year progression-free survival charges have been 12 months, 16.9%, and 11.three%, respectively; the median and 5- and 10-year total survival charges have been 18 months, 21.three%, and 12%, respectively. On univariate and multivariate evaluation, components recorded as conditioning survival have been the efficiency standing and the presence of different metastases on the time of vertebral remedy (P < zero.01).
CONCLUSIONS: Our replace confirmed that surgical procedure plus RT is a protected and possible remedy with restricted morbidity. In chosen sufferers with favorable prognostic components, the mixed remedy could considerably impression on survival.

PMID: 29709741 [PubMed – indexed for MEDLINE]

Lengthy-Time period Comply with-Up of Sufferers with Metastatic Epidural Spinal Twine Compression from Stable Tumors Submitted for Surgical procedure Adopted by Radiation Remedy | London ontario spine clinic

What our patients say ...

Consultant Spine Surgeon
Consultant Spine Surgeon
Consultant Spine Surgeon

This surgical technique consists of a percutaneous approach for the treatment of small to medium size hernias of the intervertebral disc by laser energy. The main objective is to reduce the intradiscal pressure in the nucleus pulposus

Laser Disc Surgery can be performed under local anaesthetic as a day case at our centre on the prestigious Harley Street.
What is London spine unit and How it Works

The London Spine Unit was established in 2005 and has successfully treated over 5000 patients. All conditions are treated.

treatment of all spinal disorders

The London Spine Unit specialises in Minimally Invasive Treatments allowing rapid recovery and return to normal function

Trusted by patients worldwide

The London Spine Unit provides the highest quality care to all patients and has VIP services for those seeking exceptional services

If you have any emergency Doctor’s need, simply call our 24 hour emergency

Your personal case manager will ensure that you receive the best possible care.

Call Now 

+44 844 589 2020
+44 203 973 8810