[Langerhans cell histiocytosis with vertebral involvement and soft tissue extension: clinical case].
Arch Argent Pediatr. 2016 Aug 01;114(four):e256-9
Authors: Luong TC, Scrigni A, Paglia M, Garavaglia M, Aisenberg N, Rowensztein H, Sampor C
UNLABELLED: Langerhans cell histiocytosis is a heterogeneous illness of unknown etiology characterised by proliferation of Langerhans cells. It’s a uncommon illness. Bone involvement is widespread however vertebral illness is uncommon. We current a four 12 months previous affected person with belly ache and neurologic signs. Magnetic resonance confirmed vertebra plana in D9 with involvement of paravertebral tender tissues. The kid underwent surgical procedure for decompression and biopsy. Biopsy confirmed Langerhans cell histiocytosis. She was handled with vinblastine and prednisone throughout 6 months following LCH-III with full restoration of neurologic signs.
CONCLUSION: Langerhans cell histiocytosis is a differential prognosis in a radiograph with vertebra plana or collapse of vertebral physique.
PMID: 27399028 [PubMed – indexed for MEDLINE]