Is osteoporosis a predictor for future sarcopenia or vice versa? 4-year observations between the second and third ROAD examine surveys.
Osteoporos Int. 2017 Jan;28(1):189-199
Authors: Yoshimura N, Muraki S, Oka H, Iidaka T, Kodama R, Kawaguchi H, Nakamura Okay, Tanaka S, Akune T
In a Four-year follow-up examine that enrolled 1099 topics aged ?60 years, sarcopenia prevalence was estimated at eight.2%. Furthermore, the presence of osteoporosis was considerably related to short-term sarcopenia incidence, however the reciprocal relationship was not noticed, suggesting that osteoporosis would enhance the chance of osteoporotic fracture and sarcopenia incidence.
INTRODUCTION: The current Four-year follow-up examine was carried out to make clear the prevalence, incidence, and relationships between sarcopenia (SP) and osteoporosis (OP) in older Japanese women and men.
METHODS: We enrolled 1099 contributors (aged, ?60 years; 377 males) from the second survey of the Analysis on Osteoarthritis/Osteoporosis towards Incapacity (ROAD) examine (2008-2010) and adopted them up for Four years. Handgrip power, gait velocity, skeletal muscle mass, and bone mineral density have been assessed. SP was outlined in accordance with the Asian Working Group for Sarcopenia. OP was outlined primarily based on the World Well being Group standards.
RESULTS: SP prevalence was eight.2% (males, eight.5%; girls, eight.zero%) within the second survey. In these with SP, 57.eight% (21.9%; 77.6%) had OP on the lumbar backbone L2-Four and/or femoral neck. SP cumulative incidence was 2.zero%/yr (2.2%/yr; 1.9%/yr). Multivariate regression evaluation revealed that OP was considerably related to SP incidence inside Four years (odds ratio, 2.99; 95% confidence interval, 1.46-6.12; p < zero.01), however the reciprocal relationship was not considerably noticed (2.11; zero.59-7.59; p = zero.25).
CONCLUSIONS: OP may elevate the short-term danger of SP incidence. Due to this fact, OP wouldn’t solely enhance the chance for osteoporotic fracture however can also enhance the chance for SP incidence.
PMID: 27885410 [PubMed – indexed for MEDLINE]