19 Harley St, London, W1G 9QJ, UK

Is anterior bone loss the opposite of anterior heterotopic ossification in Prestige-LP cervical disc replacement?

Icon for Elsevier Science Related Articles

Is anterior bone loss the opposite of anterior heterotopic ossification in Prestige-LP cervical disc replacement?

World Neurosurg. 2020 Jan 10;:

Authors: Wang X, Meng Y, Liu H, Hong Y, Wang B

Abstract
BACKGROUND: Heterotopic ossification (HO) and anterior bone loss (ABL) are two complications in cervical disc replacement (CDR), which have impacts on the clinical outcomes. Physiologically, bone formation (HO) and bone loss are two sides of bone remodeling. However, clinically, some patients occurred anterior HO (AHO) after CDR, while other patients occurred ABL. Is there any factor in determining the fate of the vertebral bone in the anterior region? Is ABL the opposite of AHO? This study aims to answer the above questions.
METHODS: Seventy patients with one-level Prestige-LP CDR were retrospectively reviewed and were divided into AHO group or ABL group. Radiological outcomes, including cervical lordosis, sagittal vertical axis (SVA), functional spine unit (FSU) angle, disc angle, range of motion (ROM), implant migration, subsidence, adjacent segment degeneration (ASD) were evaluated. Patient-reported clinical outcomes were also evaluated.
RESULTS: AHO group showed significantly lower disc angle after surgery (0.9±4.2˚), compared to ABL group (6.7±4.7˚) (p<0.001). The preoperative segmental ROM was significantly higher in AHO group (10.2±3.3˚) than that in ABL group (8.2±3.7˚) (p=0.042). No correlation was observed between clinical outcomes and the presence of anterior bone remodeling. Both groups maintained cervical alignment and FSU angle during long-term follow-up. No significant difference was found in the endplate preparation, implant subsidence, migration, or ASD rate between the two groups.
CONCLUSIONS: The differences in the disc angle showed the role of mechanical load in the anterior bone remodeling. Combined the results with the basic concepts of bone remodeling, ABL may be the opposite of AHO.

PMID: 31931240 [PubMed – as supplied by publisher]

Is anterior bone loss the opposite of anterior heterotopic ossification in Prestige-LP cervical disc replacement? Heterotopic ossification (HO) and anterior bone loss (ABL) are two complications in cervical disc replacement (CDR), which have impacts on…

What our patients say ...

Consultant Spine Surgeon
Consultant Spine Surgeon
Consultant Spine Surgeon

This surgical technique consists of a percutaneous approach for the treatment of small to medium size hernias of the intervertebral disc by laser energy. The main objective is to reduce the intradiscal pressure in the nucleus pulposus

Laser Disc Surgery can be performed under local anaesthetic as a day case at our centre on the prestigious Harley Street.
What is London spine unit and How it Works

The London Spine Unit was established in 2005 and has successfully treated over 5000 patients. All conditions are treated.

treatment of all spinal disorders

The London Spine Unit specialises in Minimally Invasive Treatments allowing rapid recovery and return to normal function

Trusted by patients worldwide

The London Spine Unit provides the highest quality care to all patients and has VIP services for those seeking exceptional services

If you have any emergency Doctor’s need, simply call our 24 hour emergency

Your personal case manager will ensure that you receive the best possible care.

Call Now 

+44 844 589 2020
+44 203 973 8810