Intradural spinal tumors in adults-update on administration and final result.
Neurosurg Rev. 2018 Feb 17;:
Authors: Ottenhausen M, Ntoulias G, Bodhinayake I, Ruppert FH, Schreiber S, Förschler A, Boockvar JA, Jödicke A
Amongst spinal tumors that happen intradurally, meningiomas, nerve sheath tumors, ependymomas, and astrocytomas are the most typical. Whereas a spinal MRI is the state-of-the-art to diagnose intradural spinal tumors, in some circumstances CT scans, angiography, CSF analyses, and neurophysiological examination could be worthwhile. The administration of those lesions relies upon not solely on the histopathological prognosis but in addition on the medical presentation and the anatomical location, permitting both radical resection as with most extramedullary lesions or much less invasive methods as with intramedullary lesions. Though intramedullary lesions are uncommon and generally troublesome to handle, well-planned therapy can obtain wonderful final result with out treatment-related deficits. Technical advances in imaging, neuromonitoring, minimally invasive approaches, and radiotherapy have improved the end result of intradural spinal tumors. Nonetheless, the end result in malignant intramedullary tumors stays poor. Whereas surgical procedure is the mainstay therapy for a lot of of those lesions, radiation and chemotherapy are of rising significance in recurrent and multilocular illness. We reviewed the literature on this matter to supply an outline of spinal wire tumors, therapy methods, and outcomes. Typical circumstances of extra- and intramedullary tumors are introduced as an instance administration choices and outcomes.
PMID: 29455369 [PubMed – as supplied by publisher]