Intradural spinal tumors in adults-update on administration and end result.
Neurosurg Rev. 2018 Feb 17;:
Authors: Ottenhausen M, Ntoulias G, Bodhinayake I, Ruppert FH, Schreiber S, Förschler A, Boockvar JA, Jödicke A
Amongst spinal tumors that happen intradurally, meningiomas, nerve sheath tumors, ependymomas, and astrocytomas are the commonest. Whereas a spinal MRI is the state-of-the-art to diagnose intradural spinal tumors, in some instances CT scans, angiography, CSF analyses, and neurophysiological examination will be worthwhile. The administration of those lesions relies upon not solely on the histopathological prognosis but in addition on the scientific presentation and the anatomical location, permitting both radical resection as with most extramedullary lesions or much less invasive methods as with intramedullary lesions. Though intramedullary lesions are uncommon and generally tough to handle, well-planned remedy can obtain glorious end result with out treatment-related deficits. Technical advances in imaging, neuromonitoring, minimally invasive approaches, and radiotherapy have improved the result of intradural spinal tumors. Nevertheless, the result in malignant intramedullary tumors stays poor. Whereas surgical procedure is the mainstay remedy for a lot of of those lesions, radiation and chemotherapy are of rising significance in recurrent and multilocular illness. We reviewed the literature on this subject to supply an outline of spinal wire tumors, remedy methods, and outcomes. Typical instances of extra- and intramedullary tumors are offered for instance administration choices and outcomes.
PMID: 29455369 [PubMed – as supplied by publisher]