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Intervertebral (Lumbar) Disc Replacement:the Current State And Future Perspectives – Lumbar Disc Replacement

The article discusses the current state of treatments for degenerative disc disease, focusing on the use of total disc replacements and comparing them to fusion methods. The authors conducted a critical review of scientific articles, finding that total disc replacements have not yet proven to be superior to fusion methods in long-term follow-up. The article also highlights the potential of advanced methods such as regenerative and gene therapy, as well as 3D printing, in treating degenerative disc disease. However, further research and development are still necessary for total disc replacements, and conservative treatments and primary prevention should also be emphasized

Summarised by Mr Mo Akmal – Lead Spinal Surgeon
The London Spine Unit : innovative day surgery hospital on Harley Street UK

Published article

CONCLUSIONS: Additional research and development of total disc replacements is still necessary. For implants, the 3D scan – 3D model – 3D printing chain and its related technologies are increasingly important. The development of regenerative procedures using induced pluripotent stem cells and gene therapies is important, but conservative treatments and primary prevention should also be developed because regenerative procedures and gene therapies apparently will not be used routinely until the…

Lumbar Disc Replacement Surgery Expert. Best Spinal Surgeon UK
Abstract Purpose: Low back pain is a significant socio-economic problem which is expected to deepen. Degenerative disc disease is considered to be one of its main causes. Unsuccessful conservative treatments usually lead to surgical treatments, including methods providing pain relief by vertebral fusion in the affected segment. However, this leads to changes in biomechanics, which,

Abstract

Purpose: Low back pain is a significant socio-economic problem which is expected to deepen. Degenerative disc disease is considered to be one of its main causes. Unsuccessful conservative treatments usually lead to surgical treatments, including methods providing pain relief by vertebral fusion in the affected segment. However, this leads to changes in biomechanics, which is why approximately 30 years ago total disc replacements appeared. This work aims at determining the current state of treatments with this kind of replacement, comparing the results with those of fusion methods and assessing why fusion continues to dominate. Current treatments of degenerative disc disease by advanced procedures (regenerative and gene therapy, 3D printing) is also examined and evaluated, and future developments are considered.

Methods: A critical review based on available scientific articles from online databases. The main keywords used were “lumbar”, “total”, “disc” and “replacement”, supplemented according to the individual, monitored areas (“follow-up”, “fusion”, “future” etc.). For the articles found through database search (n = 895), narrower selection was made and the result was 33 articles included in review.

Review: Total disc replacements have not yet satisfactorily demonstrated that they are superior to fusion methods in long term follow-up. Advanced methods are in their infancy.

Conclusions: Additional research and development of total disc replacements is still necessary. For implants, the 3D scan – 3D model – 3D printing chain and its related technologies are increasingly important. The development of regenerative procedures using induced pluripotent stem cells and gene therapies is important, but conservative treatments and primary prevention should also be developed because regenerative procedures and gene therapies apparently will not be used routinely until the future.

The London Spine Unit : innovative day surgery hospital on Harley Street UK

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Intervertebral (lumbar) disc replacement:the current state and future perspectives

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Abstract Purpose: Low back pain is a significant socio-economic problem which is expected to deepen. Degenerative disc disease is considered to be one of its main causes. Unsuccessful conservative treatments usually lead to surgical treatments, including methods providing pain relief by vertebral fusion in the affected segment. However, this leads to changes in biomechanics, which

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